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Adipose-Renal Axis in Diabetic Nephropathy

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机构： [1]Department of Nutrition, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, People\\\'s Republic of China. [2]Department of Nephrology, The Second Xiangya Hospital of Central South University, Changsha, China. [3]Department of Reproduction and Genetics, the First Affiliated Hospital of Kunming Medical University. [4]Department of Nutrition, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, People\'s Republic of China. [5]National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.

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Long-term diabetes can lead to renal injury known as diabetic nephropathy (DN), which is a major cause of end-stage renal disease (ESRD). However, its pathogenesis has not been well explained. Adipose tissue is recognized as an important energy storage device for the body. Interestingly, many studies have shown that adipose tissue can also act as an endocrine organ by secreting a variety of adipokines to maintain homeostasis. Here, we summarize some of the adipokines that have been identified thus far to, more specifically, to emphasize their role in DN progression and propose that the "adipose-renal axis" may be a potential target for the treatment of DN.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

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最新[2023]版

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大类 | 4 区医学

小类 | 3 区生化与分子生物学 3 区药物化学 3 区药学

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出版当年[2023]版：

Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Q2 CHEMISTRY, MEDICINAL Q2 PHARMACOLOGY & PHARMACY

最新[2023]版：

Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Q2 CHEMISTRY, MEDICINAL Q2 PHARMACOLOGY & PHARMACY

影响因子： 3.5 最新[2023版] 4 最新五年平均 3.5 出版当年[2023版] 4 出版当年五年平均 4.1 出版前一年[2022版]

第一作者：

第一作者机构： [1]Department of Nutrition, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, People\\\'s Republic of China. [2]Department of Nephrology, The Second Xiangya Hospital of Central South University, Changsha, China.

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