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Chinese Guideline on Allergen Immunotherapy for Allergic Rhinitis: The 2022 Update

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机构： [1]Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China. [2]Beijing Key Laboratory of Nasal Diseases and Beijing Laboratory of Allergic Diseases, Beijing Institute of Otorhinolaryngology, Beijing, China. [3]Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, China. [4]Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, China. [5]Shanghai Tonxin Clinic, Shanghai, China. [6]Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China. [7]Department of Pulmonary and Critical Care Medicine, Second Affiliated Hospitial of Fujian Medical University, Respiratory Medicine Center of Fujian Province, Quanzhou, China. [8]Department of Otorhinolaryngology & Clinical Allergy Center, The First Affiliated Hospital, Nanjing Medical University, Nanjing, China. [9]Department of Allergy & Immunology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. [10]Department of Respiratory Diseases, Children's Hospital of Soochow University, Suzhou, China. [11]Department of Allergy, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. [12]Department of Otolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China. [13]Department of Allergy and Clinical Immunology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. [14]Department of Pediatrics, The Second Hospital of Tianjin Medical University, Tianjin, China. [15]Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. [16]Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. [17]Department of Otorhinolaryngology, Peking Union Medical College Hospital, Beijing, China. [18]Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China. [19]Department of Otolaryngology-Head and Neck Surgery, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China. [20]Department of Otorhinolaryngology Head and Neck Surgery, The Second Hospital of Hebei Medical University, Shijiazhuang, China. [21]Department of Pediatrics, Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. [22]Department of Respiratory Diseases, The First Affiliated Hospital of College of Medicine, Zhejiang University, Hangzhou, China. [23]Department of Otolaryngology,The Second Hospital of Shandong University, Jinan, China. [24]Department of Otorhinolaryngology Head and Neck Surgery, Yuhuangding Hospital of Qingdao University, Yantai, China. [25]Department of Allergy, Harbin Children's Hospital, Harbin, China. [26]Department of Allergy, Fuzhou Children's Hospital Affiliated to Fujian Medical University, Fuzhou, China. [27]Department of Allergy, Beijing ShiJiTan Hospital, Capital Medical University, Beijing, China. [28]Department of Otorhinolaryngology Head and Neck Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China. [29]Department of Allergy, Shengjing Hospital of China Medical University, Shenyang, China. [30]Department of Allergy, Northern Theatre General Hospital, Shenyang, China. [31]Department of Otolaryngology-Head and Neck Surgery, Peking University People's Hospital, Beijing, China. [32]Department of Allergy of Otorhinolaryngology Hospital, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China. [33]Department of Otorhinolaryngology Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, China. [34]Department of Otolaryngology-Head and Neck Surgery, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China. [35]Department of Respiratory and Critical Care Medicine, Guizhou Provincial People's Hospital, Guiyang, China. [36]Department of Otorhinolaryngology Head and Neck Surgery, The First Affiliated Hospital of Nanchang University, Nanchang, China. [37]Department of Otolaryngology Head and Neck Surgery, Affiliated Hospital of Nantong University, Nantong, China. [38]Department of Otorhinolaryngology, The First Affiliated Hospital of Kunming Medical University, Kunming, China. [39]Department of Allergy, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, China. [40]Department of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. [41]Department of Allergy, Chongqing General Hospital, Chongqing, China. [42]Department of Otorhinolaryngology, The Third Hospital of Peking University, Beijing, China. [43]Department of Otorhinolaryngology Head and Neck Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China. [44]Department of Allergy, The Second Affiliated Hospital of Harbin Medical University, Harbin, China. [45]Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, China

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In the last few decades, there has been a progressive increase in the prevalence of allergic rhinitis (AR) in China, where it now affects approximately 250 million people. AR prevention and treatment include allergen avoidance, pharmacotherapy, allergen immunotherapy (AIT), and patient education, among which AIT is the only curative intervention. AIT targets the disease etiology and may potentially modify the immune system as well as induce allergen-specific immune tolerance in patients with AR. In 2017, a team of experts from the Chinese Society of Allergy (CSA) and the Chinese Allergic Rhinitis Collaborative Research Group (C2AR2G) produced the first English version of Chinese AIT guidelines for AR. Since then, there has been considerable progress in basic research of and clinical practice for AIT, especially regarding the role of follicular regulatory T (TFR) cells in the pathogenesis of AR and the use of allergen-specific immunoglobulin E (sIgE) in nasal secretions for the diagnosis of AR. Additionally, potential biomarkers, including TFR cells, sIgG4, and sIgE, have been used to monitor the incidence and progression of AR. Moreover, there has been a novel understanding of AIT during the coronavirus disease 2019 pandemic. Hence, there was an urgent need to update the AIT guideline for AR by a team of experts from CSA and C2AR2G. This document aims to serve as professional reference material on AIT for AR treatment in China, thus improving the development of AIT across the world.Copyright © 2022 The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease.

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中科院(CAS)分区：

出版当年[2023]版：

大类 | 2 区医学

小类 | 2 区免疫学 3 区过敏

最新[2023]版：

大类 | 2 区医学

小类 | 2 区免疫学 3 区过敏

JCR分区：

出版当年[2022]版：

Q2 ALLERGY Q2 IMMUNOLOGY

最新[2023]版：

Q2 ALLERGY Q2 IMMUNOLOGY

影响因子： 4.1 最新[2023版] 4.8 最新五年平均 4.4 出版当年[2022版] 4.6 出版当年五年平均 5.096 出版前一年[2021版] 4.1 出版后一年[2023版]

第一作者：

第一作者机构： [1]Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China. [2]Beijing Key Laboratory of Nasal Diseases and Beijing Laboratory of Allergic Diseases, Beijing Institute of Otorhinolaryngology, Beijing, China. [3]Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, China. [4]Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, China.

共同第一作者：

通讯作者：

通讯机构： [1]Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China. [45]Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, China

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