个人科研网厅 | | 帮助
高级检索
当前位置： 首页 > 详情页

Combined simultaneous transsphenoidal and transcranial regimen improves surgical outcomes in complex giant pituitary adenomas: A longitudinal retrospective cohort study

| 导出 | |

文献详情

资源类型：
WOS体系：
Pubmed体系：

收录情况： ◇ SCIE

作者：
Qiao Nidan[1,2,3,4,5] * ; Gao Wei[6] * ; Deng Xingli[7] * ; Xin Tao[8] * ; Zhang Gangli[9] * ; Wu Nan[10] * ; Wang Pan[10] ; Bi Yunke[11] ; Cong Zixiang[12] ; Zhou Zhiyi[13] ; Li Junjun[7] ; Sun Shengyu[14] ; Li Meng[8] ; Tang Wenlong[15] ; Yan Xiaorong[16] ; Wang Wenxiong[9] ; Chou Wenjin[17] ; Yao Shun[1,2,3,4,5] ; Ye Zhao[1,2,3,4,5] ; Ma Zengyi[1,2,3,4,5] ; Zhou Xiang[1,2,3,4,5] ; Cao Xiaoyun[1,2,3,4,5] ; Shen Ming[1,2,3,4,5] ; Shou Xuefei[1,2,3,4,5] ; Zhang Zhaoyun[18] ; Wu Zhenyu[19] ; Chu Liangzhao[17] ; Qiu Yongming[13] ; Ma Hui[14] ; Wu Anhua[6] ; Ma Chiyuan[12] ; Lou Meiqing[11] ; Jiang Changzhen[16,*1] ; Wang Yongfei[1,2,3,4,5,*2] ; Zhao Yao[1,2,3,4,5,20,*2] ;
机构： [1]Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China. [2]National Center for Neurological Disorders, Shanghai, China. [3]State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China. [4]Shanghai Key laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China. [5]Neurosurgical Institute of Fudan University, Shanghai, China. [6]Department of Neurosurgery, Shenjing Hospital of China Medical University, Shenyang, Liaoning, China. [7]Department of Neurosurgery, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China. [8]Department of Neurosurgery, The First Affiliated Hospital of Shandong First Medical University, Jinan, Shandong, China. [9]Department of Neurosurgery, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China. [10]Department of Neurosurgery, Chongqing General Hospital, Chongqing, China. [11]Department of Neurosurgery, Shanghai General Hospital, Shanghai, China. [12]Department of Neurosurgery, General Hospital of Eastern Theater Command (Nanjing Jinlin Hospital), Nanjing, Jiangsu, China. [13]Department of Neurosurgery, Renji Hospital, Shanghai, China. [14]Department of Neurosurgery, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China. [15]Department of Neurosurgery, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, Shanxi, China. [16]Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China. [17]Department of Neurosurgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China. [18]Department of Endocrinology, Huashan Hospital, Fudan University, Shanghai, China. [19]School of Public Health, Fudan University, Shanghai, China. [20]National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China.
出处：
DOI： 10.1097/JS9.0000000000001330
ISSN：

关键词： Neuroendocrine pituitary surgery causal inference regimen

摘要：
Surgical treatment of complex giant pituitary adenomas (GPAs) presents significant challenges. The efficacy and safety of combining transsphenoidal and transcranial approaches for these tumors remain controversial. In this largest cohort of patients with complex GPAs, we compared the surgical outcomes between those undergoing a combined regimen and a non-combined regimen. We also examined the differences in risks of complications, costs, and logistics between the two groups, which might offer valuable information for the appropriate management of these patients.This was a multicenter retrospective cohort study conducted at 13 neurosurgical centers. Consecutive patients who received a combined or non-combined regimen for complex GPAs were enrolled. The primary outcome was gross total resection, while secondary outcomes included complications, surgical duration, and relapse. A propensity score-based weighting method was used to account for differences between the groups.Out of 647 patients (298 [46.1%] women, mean age: 48.5 ± 14.0 years) with complex GPAs, 91 were in the combined group and 556 were in the non-combined group. Compared with the non-combined regimen, the combined regimen was associated with a higher probability of gross total resection (50.5% vs. 40.6%, odds ratio [OR]: 2.18, 95% confidence interval [CI]: 1.30-3.63, P = 0.003). The proportion of patients with life-threatening complications was lower in the combined group than in the non-combined group (4.4% vs. 11.2%, OR: 0.25, 95% CI: 0.08-0.78, P = 0.017). No marked differences were found between the groups in terms of other surgical or endocrine-related complications. However, the combined regimen exhibited a longer average surgery duration of 1.3 h (P < 0.001) and higher surgical costs of 22,000 CNY (approximate 3,000 USD, P = 0.022) compared with the non-combined approach.The combined regimen offered increased rates of total resection and decreased incidence of life-threatening complications, which might be recommended as the first-line choice for these patients.Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.

语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2025]版：
无
最新[2023]版：
大类 | 2 区 医学
小类 | 2 区 外科
JCR分区：
出版当年[2024]版：
无
最新[2023]版：
Q1 SURGERY

影响因子： 最新[2023版] 最新五年平均 出版当年[2024版] 出版当年五年平均 出版前一年[2023版]

第一作者：
第一作者机构： [1]Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China. [2]National Center for Neurological Disorders, Shanghai, China. [3]State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China. [4]Shanghai Key laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China. [5]Neurosurgical Institute of Fudan University, Shanghai, China.
共同第一作者：
通讯作者：
通讯机构： [1]Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China. [2]National Center for Neurological Disorders, Shanghai, China. [3]State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China. [4]Shanghai Key laboratory of Brain Function Restoration and Neural Regeneration, Shanghai, China. [5]Neurosurgical Institute of Fudan University, Shanghai, China. [16]Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China. [20]National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, Shanghai, China. [*1]20 Chazhong Road, Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fujian, China [*2]12 Wulumuqi Zhong Road, Department of Neurosurgery, Huashan Hospital, Shanghai, PR China
推荐引用方式(GB/T 7714)：
Qiao Nidan,Gao Wei,Deng Xingli,et al.Combined simultaneous transsphenoidal and transcranial regimen improves surgical outcomes in complex giant pituitary adenomas: A longitudinal retrospective cohort study[J].International Journal Of Surgery (London, England).2024,110(7):4043-4052.doi:10.1097/JS9.0000000000001330.
APA：
Qiao Nidan,Gao Wei,Deng Xingli,Xin Tao,Zhang Gangli...&Zhao Yao.(2024).Combined simultaneous transsphenoidal and transcranial regimen improves surgical outcomes in complex giant pituitary adenomas: A longitudinal retrospective cohort study.International Journal Of Surgery (London, England),110,(7)
MLA：
Qiao Nidan,et al."Combined simultaneous transsphenoidal and transcranial regimen improves surgical outcomes in complex giant pituitary adenomas: A longitudinal retrospective cohort study".International Journal Of Surgery (London, England) 110..7(2024):4043-4052

相关文献

[1]经鼻蝶显微手术治疗垂体脓肿13例临床分析 [2]经单鼻孔蝶窦入路显微镜下切除垂体腺瘤 [3]Exploring genetic associations between metabolites and atopic dermatitis: insights from bidirectional Mendelian randomization analysis in European population [4]New Chemotherapy Regimen in the Treatment of Advanced Gallbladder Carcinoma [5]The causal relationship between serum metabolites and acne vulgaris: a Mendelian randomization study [6]Exploring the genetic associations and causal relationships between antibody responses, immune cells, and various types of breast cancer [7]抑郁症患者神经内分泌改变与临床特征的相关性 [8]Retrospective analysis of the clinicopathological characteristics of gastrointestinal neuroendocrine neoplasms [9]会厌神经内分泌癌2例 [10]小肠神经内分泌肿瘤研究进展

资源点击量：56919 今日访问量：0 总访问量：1772 更新日期：2025-01-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 昆明医科大学第一附属医院 技术支持：重庆聚合科技有限公司 地址：云南省昆明市西昌路295号(650032)