机构：[1]Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Kunming, Yunnan, P. R. China[2]Department of Colorectal Surgery, Yunnan Cancer Hospital & The Third Affiliated Hospital of Kunming Medical University &Yunnan Cancer Center, Kunming, Yunnan, P. R. China[3]CAS Key Laboratory of Tropical Plant Resources and Sustainable Use, Yunnan Key Laboratory of Crop Wild Relatives Omics, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Kunming, Yunnan, P. R. China[4]Department of Oncology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P. R. China内科科室肿瘤内科昆明医科大学附属第一医院
Viroids, the smallest known infectious agents, were initially discovered in plants [1], and have caused significant agricultural diseases [2-4]. Recently, viroids have been identified in fungi [5-7] and bacteria [8], but none have been identified in animals. To date, no studies have explored the presence of viroids in colorectal cancer (CRC). We employed a reference-free computational method to identify a novel viroid-like circular RNA (circRNA) in CRC patients. Our study suggests that a broader class of viroids may exist in living systems.
基金：
National Natural Science Foundation of China (No. 31500748) and
the CAMS Innovation Fund for Medical Sciences (No.2017-I2M-3-022).
第一作者机构：[1]Institute of Medical Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Kunming, Yunnan, P. R. China
通讯作者：
推荐引用方式(GB/T 7714)：
Wu Meini,Li Wenliang,Hu Ningzhu,et al.Discovery of a novel viroid-like circular RNA in colorectal cancer[J].CANCER COMMUNICATIONS.2024,doi:10.1002/cac2.12626.
APA：
Wu, Meini,Li, Wenliang,Hu, Ningzhu,Liu, Changning,Li, Jianfang...&Hu, Yunzhang.(2024).Discovery of a novel viroid-like circular RNA in colorectal cancer.CANCER COMMUNICATIONS,,
MLA：
Wu, Meini,et al."Discovery of a novel viroid-like circular RNA in colorectal cancer".CANCER COMMUNICATIONS .(2024)
