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Research progress on the application of nanomaterials in the diagnosis and treatment of venous thromboembolism

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收录情况： ◇ SCIE

作者：
Wang Xiaolan[1] * ; Xu Shuanglan[2] * ; Liu Qian[1] ; Ye Xiulin[1] ; He Huilin[1] ; Zhang Xifeng[1] ; Chen Linna[1] ; Yang Jiao[1] ; Xing Xiqian[2] ;
机构： [1]Department of Pulmonary and Critical Care Medicine, First Affiliated Hospital of Kunming Medical University, 650032 Kunming, Yunnan, China [2]Department of Pulmonary and Critical Care Medicine, The Affiliated Hospital of Yunnan University, Key Laboratory of Respiratory Disease Research of Department of Education of Yunnan Province, 650021 Kunming, Yunnan, China
出处：
DOI： 10.1016/j.nano.2025.102820
ISSN：

关键词： Biosensors Drug delivery systems Nanomedicine Venous thromboembolism Nanomaterials

摘要：
Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a serious vascular disease with hidden symptoms and rapid progression. Nanomaterials provide new ideas for the diagnosis and treatment of VTE due to their high specific surface area, biocompatibility and modifiability. Due to differences in the formation mechanism and location of arterial and venous thrombosis, targeted diagnosis and treatment strategies need to be developed. This review focuses on VTE and summarizes the latest progress and limitations of nanomaterials in diagnosis and treatment. In terms of diagnosis, nanomaterials can be used to prepare biosensors to detect thrombin, fibrin, etc., and can also enhance imaging contrast to improve diagnostic accuracy. In terms of treatment, nanocarriers can target and release anticoagulant/thrombolytic drugs, improving efficacy and reducing side effects. However, the limitations of nanomaterials require researchers to optimize their properties to achieve safe and efficient development of VTE diagnosis and treatment.Copyright © 2025 Elsevier Inc. All rights reserved.

基金：
This study was supported by a grant from the National Natural Science Foundation of China (No. 82160016), the Special and Joint Program of the Yunnan Provincial Science and Technology Department and Kunming Medical University (No. 202201AY070001-265 and 202301AY070001-189), Famous Doctors of High-level Talent Training Support Program of Yunnan Province (No. YNWR-MY-2020-013 and XDYC-YLWS-2023-0043), Yunnan Provincial Innovation Team for Respiratory and Pulmonary Circulation Diseases (No. 202405AS350018), Yunnan Fundamental Research Projects (No. 202501CF070056), Science Research Foundation of Yunnan Provincial Education Department (No. 2024J0016), and Yunnan University Medical Research Foundation (No. YDYXJJ2024-0026).
语种：
外文
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中科院(CAS)分区：
出版当年[2026]版：
无
最新[2025]版：
大类 | 3 区 医学
小类 | 3 区 医学：研究与实验 3 区 纳米科技
JCR分区：
出版当年[2025]版：
无
最新[2024]版：
Q2 MEDICINE, RESEARCH & EXPERIMENTAL Q2 NANOSCIENCE & NANOTECHNOLOGY

影响因子： 最新[2024版] 最新五年平均 出版当年[2025版] 出版当年五年平均 出版前一年[2024版]

第一作者：
第一作者机构： [1]Department of Pulmonary and Critical Care Medicine, First Affiliated Hospital of Kunming Medical University, 650032 Kunming, Yunnan, China
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Wang Xiaolan,Xu Shuanglan,Liu Qian,et al.Research progress on the application of nanomaterials in the diagnosis and treatment of venous thromboembolism[J].Nanomedicine : Nanotechnology, Biology, And Medicine.2025,66:102820.doi:10.1016/j.nano.2025.102820.
APA：
Wang Xiaolan,Xu Shuanglan,Liu Qian,Ye Xiulin,He Huilin...&Xing Xiqian.(2025).Research progress on the application of nanomaterials in the diagnosis and treatment of venous thromboembolism.Nanomedicine : Nanotechnology, Biology, And Medicine,66,
MLA：
Wang Xiaolan,et al."Research progress on the application of nanomaterials in the diagnosis and treatment of venous thromboembolism".Nanomedicine : Nanotechnology, Biology, And Medicine 66.(2025):102820

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