Progress on the Study of Tumor Spread Through Air Spaces in the Clinicopathological Characteristics of Lung Adenocarcinoma and Its Influence on the Surgical Treatment and Prognosis of Lung Cancer
肿瘤肺泡腔内播散(tumor spread through air spaces,STAS)作为一种新的病理侵袭方式,与诸多临床病理因素紧密相关.在肺腺癌中,微乳头和实体型病理亚型与之关系最为密切;针对早期肺腺癌存在STAS,手术类型的治疗上肺叶切除似乎优于亚肺叶切除而获益,可能上调早期肺癌的病理分期;同时,STAS与鳞癌等非小细胞肺癌(non-small cell lung cancer,NSCLC)关系密切.此外,STAS的术中冰冻切片病理检测困难,亦有争议存在.STAS作为肿瘤复发的独立危险因素,亦是提示预后不良的重要因素,本文将STAS的研究现状和进展作一综述.
