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Maternal physical activity before IVF/ICSI cycles improves clinical pregnancy rate and live birth rate: a systematic review and meta-analysis

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机构: [1]Department of reproduction and genetics, the First Affiliated Hospital ofKunming Medical University, No .295 Xi Chang road, Kunming 650032, China [2]Department of Neurology, the First Affiliated Hospital of Kunming MedicalUniversity, Kunming 650032, China
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关键词: Physical activity ART IVF/ICSI Reproductive outcome

摘要:
Objective: This meta-analysis was aimed to evaluate the association between maternal physical activity before IVF/ICSI cycles and reproductive outcomes. Methods: We searched databases of PubMed, EMBASE and Web of Science electronic databases, and ongoing trials up to November 2017 to identify studies that focused on the relationship between maternal physical activity before IVF/ICSI cycles and reproductive outcomes, including implantation rate, clinical pregnancy rate, miscarriage rate and live birth rate. Odds ratio (OR) with 95% confidence intervals, were calculated to assess the results of each outcome. Results: Eight published studies encompassing 3683 infertile couples undergoing IVF/ICSI treatment were included into the analysis. There was an increasing, but not statistically significant, trend in implantation rate for physically active women when compared with physically inactive women (OR = 1.95, 95% CI 0.99-3.83, I-2 = 77%). No significant difference was found in miscarriage rate between physically active women and physically inactive women (OR = 0.76, 95% CI 0.41-1.44, I-2 = 49%). However, rates of clinical pregnancy and live births in physically active women were significantly higher than those in physically inactive women (OR = 1.96, 95% CI 1.40, 2.73, I-2 = 42% and OR = 1.95, 95% CI 1.06-3.59, I-2 = 82%, respectively). Subgroup analysis helped to confirm these results. Conclusions: Female physical activity before IVF/ICSI cycles was associated with increased rates of clinical pregnancy and live births, whereas only a small but not statistically significant increase was found in implantation rate, and no effect was shown on miscarriage rate.

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出版当年[2019]版:
大类 | 3 区 医学
小类 | 3 区 生殖生物学 4 区 内分泌学与代谢
最新[2023]版:
大类 | 2 区 医学
小类 | 2 区 内分泌学与代谢 2 区 生殖生物学
JCR分区:
出版当年[2018]版:
Q2 REPRODUCTIVE BIOLOGY Q3 ENDOCRINOLOGY & METABOLISM
最新[2023]版:
Q1 ENDOCRINOLOGY & METABOLISM Q1 REPRODUCTIVE BIOLOGY

影响因子: 最新[2023版] 最新五年平均 出版当年[2018版] 出版当年五年平均 出版前一年[2017版] 出版后一年[2019版]

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第一作者机构: [1]Department of reproduction and genetics, the First Affiliated Hospital ofKunming Medical University, No .295 Xi Chang road, Kunming 650032, China
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