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Evaluation of the therapeutic effects of QuickOpt optimization in Chinese patients with chronic heart failure treated by cardiac resynchronization

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收录情况： ◇ SCIE

作者：
Ji Yan[1] ; Shu Zhang[2] ; Dejia Huang[3] ; Xiaolin Xue[4] ; Jing Xu[5] ; Qianmin Tao[6] ; Weize Zhang[7] ; Zheng Zhang[8] ; Wei Hua[2] ; Yanchun Liang[9] ; Baopeng Tang[10] ; Wei Xu[11] ; Geng Xu[12] ; Xuejun Ren[13] ; Jingfeng Wang[14] ; Tao Guo[15] ; Shaobin Jia[16] ; Yugang Dong[17] ; Hong Jiang[18] ; Guosheng Fu[19] ; Liguang Zhu[20] ; Lin Chen[21] ; Fuli Tian[22] ; Feng Ling[23] ; Jianmei Li[24] ; Xiaoyong Qi[25] ; Yinglu Hao[26] ; Yutang Wang[27] ; Liangrong Zheng[6] ; Xiaoqun Pu[28] ; Farong Shen[29] ; Guangping Li[30] ; Hui Li[31] ; Fang Peng[32] ;
机构： [1]Department of Cardiology, Anhui Provincial Hospital, No. 17 Lujiang Road, Hefei, 230001, China. [2]CardiacArrhythmia center, Fuwai Hospital, Chinese Academy of medical Sciences, No. 167 North Lishi Road, Beijing,100037, China. [3]Department of Cardiology, West China Hospital, Sichuan University, No. 37 Guoxue lane, Chengdu,610041, China. [4]Department of Cardiology, The First Affiliated Hospital of Xi’an Jiaotong University, No. 277 YantaWest Road, Xi’an, 710061, China. [5]Department of Cardiology, Tianjin chest hospital, No. 93 Xi’an Road, Tianjin,300051, China. [6]Department of Cardiology, The First Affiliated Hospital, Zhejiang University, No. 79 Qingchun Road,Hangzhou, 310003, China. [7]Department of Cardiology, The General Hospital of Lanzhou Military, No. 98 XiaoxihuWest Street, Lanzhou, 730050, China. [8]Department of Cardiology, The First Hospital of Lanzhou University, No.1 Donggang West Road, Lanzhou, 730000, China. [9]Department of Cardiology, The General Hospital of ShenyangMilitary, No. 83 Wenhua Road, Shenyang, 110840, China. [10]Department of Cardiology, The First Affiliated Hospitalof Xinjiang Medical University, No. 137 Liyushan South Road, Urumqi, 830054, China. [11]Department of Cardiology,Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, No. 321 ZhongshanRoad, Nanjing, 210008, China. [12]Department of Cardiology, The Second Affiliated Hospital of Zhejiang UniversitySchool of Medicine, No. 88 Jiefang Road, Hangzhou, 310009, China. [13]Department of Cardiology, Beijing AnzhenHospital, Capital Medical University, No. 2 Anzhen Road, Beijing, 100029, China. [14]Department of Cardiology, SunYat-sen Memorial Hospital of Sun Yat-sen University, No. 107 Yanjiang West Road, Guangzhou, 510120, China. [15]Department of Cardiology, The First Affiliated Hospital of Kunming Medical University, No. 295 Xichang Road,Kunming, 650032, China. [16]Department of Cardiology, General Hospital of Ningxia Medical University, No. 804Shengli South Street, Yinchuan, 750004, China. [17]Department of Cardiology, The First Affiliated Hospital of SunYat-sen University, No. 58 Zhongshan Er Road, Guangzhou, 510080, China. [18]Department of Cardiology, RenminHospital of Wuhan University, No. 99 Zhangzhidong Road, Wuhan, 430060, China. [19]Department of Cardiology, SirRun Run Shaw Hospital of Medicine, Zhejiang University, No. 3 Qingchun East Road, Hangzhou, 310020, China. [20]Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, No. 6 Shuangyong Road,Nanjing, 530021, China. [21]Department of Cardiology, Fujian Provincial Hospital, No. 134 East Street, Fuzhou,350001, China. [22]The First Department of Cardiology, The 251ST Hospital of PLA, No. 13 Jianguo Road, Zhangjiakou,075000, China. [23]Department of Cardiology, Hangzhou First People’s Hospital, No. 261 HuanSha Road, Hangzhou,310006, China. [24]Department of Cardiology, The second people’s Hospital of Yunnan Province, No. 176 QingnianRoad, Kunming, 650021, China. [25]Department of Cardiology, Hebei General Hospital, No. 348 Heping West Road,Shijiazhuang, 050051, China. [26]Department of Cardiology, People’s Hospital of Yuxi City, No. 21 Nieer Road, Yuxi,653100, China. [27]Department of Cardiology, Chinese PLA General Hospital, No. 28 Fuxing Road, Beijing, 100853,China. [28]Department of Cardiology, Xiangya Hospital Central South University, No. 87 xiangya Road, Changsha,410008, China. [29]Department of Cardiology, Zhejiang Greentown Hospital, No. 409 Gudun Road, Hangzhou,310000, China. [30]Department of Cardiology, The Second Hospital of Tianjin Medical University, No. 23 PingjiangRoad, Tianjin, 300211, China. [31]Department of Cardiology, Daqing Oilfield General Hospital, No. 9 ZhongkangStreet, Daqing, 163000, China. [32]Department of Cardiology, Shaoxing People’s Hospital, No. 568 Zhongxing NorthRoad, Shaoxing, 312000, China.
出处：
DOI： 10.1038/s41598-018-22525-0
ISSN：

摘要：
In this trial, long-term therapeutic effects and clinical improvements in Chinese chronic heart failure patients optimized by QuickOpt or echocardiography were compared for atrioventricular (AV) and interventricular (VV) delay optimizations after cardiac resynchronization therapy (CRT) with pacing (CRT-P) or with pacing and defibrillator (CRT-D) therapy. One hundred and ninety-six subjects (50%) had dilated cardiomyopathy, 108 (27.6%) had ischemic heart disease and 112 (28.6%) were hypertensive and were randomized into QuickOpt (198) or echocardiographic optimization (control) (194) groups at <= 2-weeks post-implantation. Programmed AV/VV delay was optimized at baseline and at 3 and 6 months. Left ventricular end-systolic volume (LVESV), New York Heart Association (NYHA) class, specific activity scale (SAS), and the six-minute walk tests (6MWT) were evaluated by blinded researchers at 12 months. Of the QuickOpt group, LVESV decreased significantly by 24.7% +/- 33.9% compared with baseline, while LVESV of Controls decreased by 25.1% +/- 36.1% (P = 0.924). NYHA class, SAS and 6MWT also improved similarly in both groups at 12 months. Mortality in both groups was not significantly different (11.0% vs 7.6%, P = 0.289). However, there was a significant difference in the time required for optimization by QuickOpt compared with echocardiography (3.33 +/- 3.11 vs 58.79 +/- 27.03 minutes, P < 0.000).

基金：
funding from St. Jude Medical. We sincerely thank Jihong Qu and Yanhong Li from St. Jude Medical for text revision.
语种：
外文
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中科院(CAS)分区：
出版当年[2019]版：
大类 | 3 区 综合性期刊
小类 | 3 区 综合性期刊
最新[2023]版：
大类 | 2 区 综合性期刊
小类 | 2 区 综合性期刊
JCR分区：
出版当年[2018]版：
Q1 MULTIDISCIPLINARY SCIENCES
最新[2023]版：
Q1 MULTIDISCIPLINARY SCIENCES

影响因子： 最新[2023版] 最新五年平均 出版当年[2018版] 出版当年五年平均 出版前一年[2017版] 出版后一年[2019版]

第一作者：
第一作者机构： [1]Department of Cardiology, Anhui Provincial Hospital, No. 17 Lujiang Road, Hefei, 230001, China.
通讯作者：
推荐引用方式(GB/T 7714)：
Ji Yan,Shu Zhang,Dejia Huang,et al.Evaluation of the therapeutic effects of QuickOpt optimization in Chinese patients with chronic heart failure treated by cardiac resynchronization[J].SCIENTIFIC REPORTS.2018,8(1):4259.doi:10.1038/s41598-018-22525-0.
APA：
Ji Yan,Shu Zhang,Dejia Huang,Xiaolin Xue,Jing Xu...&Fang Peng.(2018).Evaluation of the therapeutic effects of QuickOpt optimization in Chinese patients with chronic heart failure treated by cardiac resynchronization.SCIENTIFIC REPORTS,8,(1)
MLA：
Ji Yan,et al."Evaluation of the therapeutic effects of QuickOpt optimization in Chinese patients with chronic heart failure treated by cardiac resynchronization".SCIENTIFIC REPORTS 8..1(2018):4259

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