Flow pattern analysis in type B aortic dissection patients after stent-grafting repair: Comparison between complete and incomplete false lumen thrombosis
机构：[1]Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia[2]Department of Mechanical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia[3]Department of Medical Radiation Sciences, Curtin University, Perth 6845, Australia[4]Department of Medical Imaging, First Affiliated Hospital of Kunming Medical University, Yunnan, 650032, China医技科室医学影像中心昆明医科大学附属第一医院[5]Department of Vascular and Endovascular Surgery, Sir Charles Gairdner Hospital, Nedlands, Perth WA 6009, Australia[6]Centre for Population Health Research, Curtin University, Perth WA 6845, Australia[7]Faculty of Health and Medical Sciences, University of Western Australia, Crawley WA 6009, Australia[8]Department of Surgery, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia[9]KPJ Damansara Specialist Hospital, 47400 Petaling Jaya, Selangor, Malaysia
Endovascular stent graft repair has become a common treatment for complicated Stanford type B aortic dissection to restore true lumen flow and induce false lumen thrombosis. Using computational fluid dynamics, this study reports the differences in flow patterns and wall shear stress distribution in complicated Stanford type B aortic dissection patients after endovascular stent graft repair. Five patients were included in this study: 2 have more than 80% false lumen thrombosis (group 1), while 3 others had less than 80% false lumen thrombosis (group 2) within 1year following endovascular repair. Group 1 patients had concentrated re-entry tears around the abdominal branches only, while group 2 patients had re-entry tears that spread along the dissection line. Blood flow inside the false lumen which affected thrombus formation increased with the number of re-entry tears and when only small amounts of blood that entered the false lumen exited through the branches. In those cases where dissection extended below the abdominal branches (group 2), patients with fewer re-entry tears and longer distance between the tears had low wall shear stress contributing to thrombosis. This work provides an insight into predicting the development of complete or incomplete false lumen thrombosis and has implications for patient selection for treatment.
第一作者机构：[1]Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia
通讯作者：
通讯机构：[*1]Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia
推荐引用方式(GB/T 7714)：
Ab Naim Wan Naimah Wan,Ganesan Poo Balan,Sun Zhonghua,et al.Flow pattern analysis in type B aortic dissection patients after stent-grafting repair: Comparison between complete and incomplete false lumen thrombosis[J].INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING.2018,34(5):doi:10.1002/cnm.2961.
APA：
Ab Naim, Wan Naimah Wan,Ganesan, Poo Balan,Sun, Zhonghua,Lei, Jing,Jansen, Shirley...&Lim, Einly.(2018).Flow pattern analysis in type B aortic dissection patients after stent-grafting repair: Comparison between complete and incomplete false lumen thrombosis.INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING,34,(5)
MLA：
Ab Naim, Wan Naimah Wan,et al."Flow pattern analysis in type B aortic dissection patients after stent-grafting repair: Comparison between complete and incomplete false lumen thrombosis".INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING 34..5(2018)
