机构：[1]Department of Ophthalmology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.外科科室眼科昆明医科大学附属第一医院[2]Department of Dermatology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.内科科室皮肤科昆明医科大学附属第一医院[3]Office of Educational Administration, Yunnan College of Traditional Chinese Medicine, Kunming, Yunnan, China.[4]Library, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.行政科室图书馆昆明医科大学附属第一医院
Background: Deep anterior lamellar keratoplasty (DALK) is an optional treatment for patients with keratoconus, and the associated graft survival rate varies. Herein, we aimed to explore the graft survival rate of DALK in patients with keratoconus. Methods: PubMed, Web of Science, and ProQuest databases were searched to retrieve the related articles. General data, clinical characters, and graft survival rates were obtained directly from the included studies and analyzed by meta-analysis. Results: A total of 12 articles were included. The merged 1-, 3-, and 5-year graft survival rates were 100% (99.9-100%, P<.001), 92.9% (89.8-95.9%, P<.001), and 90.4% (86.0-0.948%, P<.001), respectively. Lower heterogeneity was shown in each subgroup that was divided neither according to the sample number nor number of surgeons. Conclusion: The survival rate slightly decreases year by year, but the overall trend seems relatively stable. Ensuring that all DALK procedures are performed by a single surgeon might be helpful to improve the graft survival rate after surgery.
基金：
Yunnan Health Science and Technology Project [2017NS064]
第一作者机构：[1]Department of Ophthalmology, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China.
通讯作者：
通讯机构：[*1]Department of Ophthalmology, The First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Kunming, Yunnan 650031, China
推荐引用方式(GB/T 7714)：
Guan Meng,Zhao Weijia,Zhang Yang,et al.Graft survival rate of deep anterior lamellar keratoplasty for keratoconus A meta-analysis[J].MEDICINE.2018,97(28):doi:10.1097/MD.0000000000011404.
APA：
Guan, Meng,Zhao, Weijia,Zhang, Yang,Geng, Yu,Chen, Zonghan...&Yuan, Ling.(2018).Graft survival rate of deep anterior lamellar keratoplasty for keratoconus A meta-analysis.MEDICINE,97,(28)
MLA：
Guan, Meng,et al."Graft survival rate of deep anterior lamellar keratoplasty for keratoconus A meta-analysis".MEDICINE 97..28(2018)
