机构：[1]Nanjing General Hospital of Nanjing Military Command, No305 ZhongshanEast Road, Nanjing 210002, China[2]Department of emergency medicine, SirRun Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou,China[3]Henan Provincial People’s Hospital, Zhengzhou, China[4]Zhongshan People’s Hospital, Zhongshan, China[5]Shandong University Qilu Hospital,Jinan, China[6]Changzhou No2 People’s Hospital affiliated to Nanjing MedicalUniversity, Nanjing, China[7]Jilin University First Hospital, Changchun, China[8]Xiangya Hospital Central South University, Changsha, China[9]Guizhou Medical University affiliated hospital, Guiyang, China[10]Wuxi People’sHospital, Wuxi, China[11]Hubei Provincial People’s Hospital, Wuhan, China[12]Tai’an Central Hospital, Tai’an, China[13]First Affiliated Hospital of NanchangUniversity, Nanchang, China[14]Third Military Medical University DapingHospital, Chongqing, China[15]China Medical University Second AffiliatedHospital, Shenyang, China中国医科大学盛京医院[16]Guangzhou Medical University First AffiliatedHospital, Guangzhou, China[17]Sichuan Provincial People’s Hospital, Chengdu,China四川省人民医院[18]Qingdao Municipal Hospital Group, Qingdao, China[19]Jining First People’s Hospital, Jining, China[20]Guangzhou First Municipal People’sHospital, Guangzhou, China[21]Xiehe Affiliated Hospital of Fujian MedicalUniversity, Fuzhou, China[22]Dazhou Central Hospital, Dazhou, China[23]Inner Mongolia People’s Hospital, Huhehaote, China[24]Zhejiang University Schoolof Medicine Sir Run Run Shaw Hospital, Hangzhou, China[25]Qindao University Medical College Affiliated Yantai Yuhuangding Hospital, Qingdao,China[26]Tianjing People’s Hospital, Tianjin, China[27]Tianjing First Central Hospital, Tianjin, China[28]Tangshan Gongren Hospital, Tangshan, China[29]Southern Medical University Zhujiang Hospital, Guangzhou, China南方医科大学珠江医院[30]North China University of Science and Technology Affiliated Hospital, Tangshan,China[31]Dalian Central Hospital, Dalian, China大连市中心医院[32]Peking University Third Hospital, Beijing, China[33]Anhui Medical University Second Affiliated Hospital,Hefei, China[34]Wenzhou Medical University First Affiliated Hospital, Wenzhou,China[35]Shanxi Provincial People’s Hospital, Taiyuan, China陕西省人民医院[36]Guangzhou Medical University Second Affiliated Hospital, Guangzhou, China[37]Second Affiliated Hospital of Dalian Medical University, Dalian, China[38]Zhengzhou University First Affiliated Hospital, Zhengzhou, China[39]First People’s Hospitalof Kunming, Kunming, China[40]Union Hospital Affiliated to Tongji MedicalCollege of Huanzhong University of Science and Technology, Wuhan, China华中科技大学同济医学院附属协和医院[41]Xinjiang Medical University Affiliated First Hospital, Wulumuqi, China[42]Chengdu University of Traditional Chinese Medicine Affiliated Hospital,Chengdu, China[43]First Affiliated Hospital of Anhui Medical University, Hefei,China[44]Yichang Central People’s Hospital, Yichang, China[45]Suzhou Municipal Hospital, Suzhou, China[46]Jining Medical College AffiliatedHospital, Jining, China[47]First Affiliated Hospital of Soochow University,Suzhou, China[48]Qindao University Medical College Affiliated Hospital,Qindao, China[49]Central South University Third Xiangya Hospital, Changsha,China[50]401 Military Hospital of China, Qindao, China[51]Changsha CentralHospital, Changsha, China[52]Yijishan Hospital of Wannan Medical College,Wuhu, China[53]Shanxi Medical University First Affiliated Hospital, Taiyuan,China[54]Kuming Medical University First Affiliated Hospital, Kuming, China[55]Hebei Medical University Third Affiliated Hospital, Shijiazhuang, China[56]First Affiliated Hospital of Fujian Medical University, Fuzhou, China[57]Zibo Central Hospital, Zibo, China[58]First People’s Hospital of Yichang, Yichang,China[59]Wuhan University Zhongnan Hospital, Wuhan, China[60]Wenzhou Medical University Second Affiliated Hospital, Wenzhou, China[61]Shantou University Medical College First Affiliated Hospital, Shantou, China[62]Zhongnan University Xiangya Second Hospital, Changsha, China[63]Yunnan Second People’s Hospital, Kunming, China[64]Yancheng First People’sHospital, Yancheng, China[65]First People’s Hospital of Foshan, Foshan, China[66]Chongqing Medical University First Affiliated Hospital, Chongqing, China重庆医科大学附属第一医院[67]Xi’an Jiao Tong University First Affiliated Hospital, Xi’an, China[68]Beijing Wujing General Hospital, Beijing, China[69]Shenzhen People’s Hospital,Shenzhen, China深圳市人民医院深圳医学信息中心[70]Shanxi Dayi Hospital of Shanxi Academy of MedicalScience, Taiyuan, China山西白求恩医院[71]254 Military Hospital of China, Tianjin, China[72]Qingdao University Affiliated Hospital, Qingdao, China[73]Linhai FirstPeople’s Hospital, Linhai, China[74]Tongji Hospital of Tongji Medical Collegeof Huazhong University of Science and Technology, Wuhan, China华中科技大学同济医学院附属同济医院[75]First Affiliated Hospital of Dalian Medical University, Dalian, China大连医科大学附属第一医院[76]Beijing Chaoyang Hospital, Beijing, China北京朝阳医院[77]Chongqing Medical University Second Affiliated Hospital, Chongqing, China[78]People's Hospital of Yuxi City, Yuxi,China[79]Shijitan Hospital of Capital Medical University, Beijing, China[80]Shenzhen Nanshan People’s Hospital, Shenzhen, China深圳市南山区人民医院深圳医学信息中心[81]Affiliated Hospitalof Inner Mongolia Medical College, Huhehaote, China[82]Benq Hospital,Nanjing, China[83]Luhe Hospital, Beijing, China[84]Beijing Jingmei GroupGeneral Hospital, Beijing, China[85]Jiangxi Provincial People’s Hospital,Nanchang, China[86]Jinan University First Affiliated Hospital, Jinan, China[87]General Hospital of Rocket Army, Beijing, China[88]Hebei Medical UniversitySecond Affiliated Hospital, Shijiazhuang, China[89]Binzhou Medical CollegeAffiliated Hospital, Binzhou, China[90]Chinese PLA General Hospital, Beijing,China[91]Yantai Mountain Hospital, Yantai, China[92]Tianjing Hospital ofITCWM Nankai Hospital, Tianjing, China[93]Hunan Provincial People’s Hospital,Changsha, China[94]People’s Hospital of Guangxi Zhuang AutonomousRegion, Nanning, China[95]Sun Yat-sen University Sixth Affiliated Hospital,Guangzhou, China中山大学附属第六医院[96]China Academy of Chinese Medical Sciences XiyuanHospital, Beijing, China[97]Wuhan General Hospital of Guangzhou MilitaryRegion, Wuhan, China[98]First People’s Hospital of Yunnan, Kunming, China云南省第一人民医院[99]Xinjiang Military General Hospital, Wulumuqi, China[100]Miyun Hospital ofBeijing, Beijing, China[101]Luoyang Central Hospital, Luoyang, China[102]Huairou First Hospital of Beijing, Beijing, China[103]Military General Hospitalof Beijing PLA, Beijing, China[104]Guangdong Provincial People’s Hospital,Guangzhou, China广东省人民医院[105]Guangdong Second TCM Hospital, Guangzhou, China广东省中医院[106]Beijing Hospital of TCM, Beijing, China[107]Anhui Provincial Hospital, Hefei,China[108]Shenyang First People’s Hospital, Shenyang, China[109]Guangzhou Military General Hospital, Guangzhou, China[110]Sun Yat-sen University FirstAffiliated Hospital, Guangzhou, China中山大学附属第一医院[111]Tianjing Cancer Hospital, Tianjing,China[112]Shanxi Cancer Hospital, Taiyuan, China[113]Nanchang UniversitySecond Affiliated Hospital, Nanchang, China[114]Beijing University of ChineseMedicine Affiliated Dongfang Hospital, Beijing, China[115]Shenzhen Second People’s Hospital, Shenzhen, China[116]Chendu Fifth People’s Hospital,Chendu, China
Background: There is a lack of large-scale epidemiological data on the clinical practice of enteral nutrition (EN) feeding in China. This study aimed to provide such data on Chinese hospitals and to investigate factors associated with EN delivery. Methods: This cross-sectional study was launched in 118 intensive care units (ICUs) of 116 mainland hospitals and conducted on April 26, 2017. At 00:00 on April 26, all patients in these ICUs were included. Demographic and clinical variables of patients on April 25 were obtained. The dates of hospitalization, ICU admission and nutrition initiation were reviewed. The outcome status 28 days after the day of investigation was obtained. Results: A total of 1953 patients were included for analysis, including 1483 survivors and 312 nonsurvivors. The median study day was day 7 (IQR 2-19 days) after ICU entry. The proportions of subjects starting EN within 24, 48 arid 72 h after ICU entry was 24.8% (84/352), 32.7% (150/459) and 40.0% (200/541), respectively. The proportion of subjects receiving > 80% estimated energy target within 24, 48, 72 h and 7 days after ICU entry was 10.5% (37/352), 10.9% (50/459), 11.8% (64/541) and 17.8% (162/910), respectively. Using acute gastrointestinal injury (AGI) 1 as the reference in a Cox model, patients with AGI 2-3 were associated with reduced likelihood of EN initiation (HR 0.46, 95% CI 0.353-0.599; p < 0.001). AGI 4 was significantly associated with lower hazard of EN administration (HR 0.056; 95% CI 0.008-0.398; p = 0.004). In a linear regression model, greater Sequential Organ Failure Assessment scores (coefficient - 0.002, 95% CI - 0.008 to - 0.001; p = 0.024) and male gender (coefficient - 0.144, 95% CI - 0.203 to - 0. 085; p < 0.001) were found to be associated with lower EN proportion. As compared with AGI 1, AGI 2-3 was associated with lower EN proportion (coefficient - 0206, 95% CI - 0.273 to - 0.139; p < 0.001). Conclusions: The study showed that EN delivery was suboptimal in Chinese ICUs. More attention should be paid to EN use in the early days after ICU admission.
基金：
This study was funded by The Standard Treatment to Key Diseases of Jiangsu
Social Development Programme (BE2015685).
第一作者机构：[1]Nanjing General Hospital of Nanjing Military Command, No305 ZhongshanEast Road, Nanjing 210002, China
通讯作者：
推荐引用方式(GB/T 7714)：
Juan Xing,Zhongheng Zhang,Lu Ke,et al.Enteral nutrition feeding in Chinese intensive care units: a cross-sectional study involving 116 hospitals[J].CRITICAL CARE.2018,22:doi:10.1186/s13054-018-2159-x.
APA：
Juan Xing,Zhongheng Zhang,Lu Ke,Jing Zhou,Bingyu Qin...&Weiqin Li.(2018).Enteral nutrition feeding in Chinese intensive care units: a cross-sectional study involving 116 hospitals.CRITICAL CARE,22,
MLA：
Juan Xing,et al."Enteral nutrition feeding in Chinese intensive care units: a cross-sectional study involving 116 hospitals".CRITICAL CARE 22.(2018)
医学