Little is known about the demographic and clinical differences between short and long duration of untreated bipolar disorder (DUB) in Chinese patients. This study examined the demographic and clinical features of short (<= 2 years) and long DUB (> 2 years) in China. A consecutively recruited sample of 555 patients with bipolar disorder (BD) was examined in 7 psychiatric hospitals and general hospital psychiatric units across China. Patients' demographic and clinical characteristics were collected using a standardized protocol and data collection procedure. The mean DUB was 3.2 +/- 6.0 years; long DUB accounted for 31.0% of the sample. Multivariate analyses revealed that longer duration of illness, diagnosis of BD type II, and earlier misdiagnosis of BD for major depressive disorder or schizophrenia were independently associated with long DUB. The mean DUB in Chinese BD patients was shorter than the reported figures from Western countries. The long-term impact of DUB on the outcome of BD is warranted.
基金：
Capital City Clinical Practice and Research Funding of Beijing Municipal Science & Technology Commission [Z141107002514033]; Clinical Medicine Development Funding of Beijing Municipal Administration of Hospitals [ZYLX201403, ZYLX201607]
第一作者机构：[1]Natl Clin Res Ctr Mental Disorders, Beijing, Peoples R China;[2]Capital Med Univ, Ctr Depress, Beijing Inst Brain Disorders, Beijing, Peoples R China;[3]Capital Med Univ, Beijing Anding Hosp, Mood Disorders Ctr, Beijing, Peoples R China;[4]Univ Macau, Fac Hlth Sci, Unit Psychiat, Taipa, Macao, Peoples R China;
通讯作者：
通讯机构：[1]Natl Clin Res Ctr Mental Disorders, Beijing, Peoples R China;[2]Capital Med Univ, Ctr Depress, Beijing Inst Brain Disorders, Beijing, Peoples R China;[3]Capital Med Univ, Beijing Anding Hosp, Mood Disorders Ctr, Beijing, Peoples R China;[4]Univ Macau, Fac Hlth Sci, Unit Psychiat, Taipa, Macao, Peoples R China;
推荐引用方式(GB/T 7714)：
Zhang Ling,Yu Xin,Fang Yi-Ru,et al.Duration of untreated bipolar disorder: a multicenter study[J].SCIENTIFIC REPORTS.2017,7:doi:10.1038/srep44811.
APA：
Zhang, Ling,Yu, Xin,Fang, Yi-Ru,Ungvari, Gabor S.,Ng, Chee H....&Xiang, Yu-Tao.(2017).Duration of untreated bipolar disorder: a multicenter study.SCIENTIFIC REPORTS,7,
MLA：
Zhang, Ling,et al."Duration of untreated bipolar disorder: a multicenter study".SCIENTIFIC REPORTS 7.(2017)
