机构：[1]Department of Dermatology, First Affiliated Hospital ofKunming Medical University, 295 Xichang Road, Kunming650032, Yunnan, China内科科室皮肤科昆明医科大学附属第一医院[2]Department of Plastic Surgery, Second Affiliated Hospital ofKunming Medical University, Kunming, Yunnan, China[3]Department of Biochemistry, Wheaton College, Norton,Massachusetts, USA[4]Department of Physiology, Kunming Medical University,1168 West Chunrong Road, Yuhua Avenue, ChenggongDistrict, Kunming 650500, Yunnan, China
Fibrosis is a common pathological state characterized by the excessive accumulation of extracellular matrix components, but the pathogenesis of the disease is still not clear. Previous studies have shown that microRNA-29 (miR-29) can play pivotal roles in the regulation of a variety of organ fibrosis, including cardiac fibrosis, hepatic fibrosis, lung fibrosis, systemic sclerosis, and keloid. In this review, we outline the structure, expression, and regulation of miR-29 as well as its role in fibrotic diseases.
基金：
National Natural Science Foundation of China (NSFC)National Natural Science Foundation of China [81560502]; National Natural Science Foundation of Yunnan Province [2013FB044, 2014FB008]; Education Department Fund of Yunnan Province [2014Y165, 2015Z082]; Doctoral Graduate Academic Newcomer Award of Yunnan Province
第一作者机构：[1]Department of Dermatology, First Affiliated Hospital ofKunming Medical University, 295 Xichang Road, Kunming650032, Yunnan, China
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Deng Zhenjun,He Yongjing,Yang Xujuan,et al.MicroRNA-29: A Crucial Player in Fibrotic Disease[J].MOLECULAR DIAGNOSIS & THERAPY.2017,21(3):285-294.doi:10.1007/s40291-016-0253-9.
APA：
Deng, Zhenjun,He, Yongjing,Yang, Xujuan,Shi, Hang,Shi, Ao...&He, Li.(2017).MicroRNA-29: A Crucial Player in Fibrotic Disease.MOLECULAR DIAGNOSIS & THERAPY,21,(3)
MLA：
Deng, Zhenjun,et al."MicroRNA-29: A Crucial Player in Fibrotic Disease".MOLECULAR DIAGNOSIS & THERAPY 21..3(2017):285-294
