机构：[a]Sichuan Academy of Medical Science & Sichuan Provincial People’s Hospital, Chengdu, Sichuan, China四川省人民医院[b]The Center of Clinical Diagnosis Laboratory, 302 Hospital of PLA, Beijing, China四川省人民医院[c]Department of Laboratory Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China医技科室医学检验科昆明医科大学附属第一医院[d]Department of Laboratory Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China医技科室医学检验科中山大学附属第一医院[e]Center of Medical Laboratory, the General Hospital of Ningxia Medical University, Yinchuan, China其他科室检验科医学检验部中山大学附属第一医院[f]Department of Laboratory Medicine, The Traditional Chinese Medical Hospital of Guangdong, Guangzhou, Guangdong, China[g]Department of Clinical Laboratory, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, Chinag苏州大学附属第二医院[h]Public Health Research Institute Tuberculosis Center, New Jersey Medical School, Rutgers University, Newark, New Jersey, USA苏州大学附属第二医院[i]Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USAi
The spread of the plasmid-mediated colistin resistance gene, mcr-1, into carbapenem-resistant Enterobacteriaceae (CRE) clinical isolates poses a significant threat to global health. Here we report the identification of three mcr-1-harboring carbapenem-resistant Escherichia coli strains, collected from three patients in two provinces in China. Our results show that mcr-1-harboring CRE strains have started to spread in different hospitals in China. In addition, this report presents the first description of chromosomal integration of mcr-1 into a carbapenem-resistant E. coli strain.
基金：
HHS |NIH| National Institute of Allergy and Infectious Diseases (NIAID) [R01AI090155, R21AI117338]; National Natural Science Foundation of China (NSFC)National Natural Science Foundation of China [81572032, 81460322, 81572058]; Chinese Military Medical and Technology Twelfth Five-Year Science and Research Key Program Fund [BWS11C073]
第一作者机构：[a]Sichuan Academy of Medical Science & Sichuan Provincial People’s Hospital, Chengdu, Sichuan, China
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Hua Yu,Fen Qu,Bin Shan,et al.Detection of the mcr-1 Colistin Resistance Gene in Carbapenem-Resistant Enterobacteriaceae from Different Hospitals in China[J].ANTIMICROBIAL AGENTS AND CHEMOTHERAPY.2016,60(8):5033-5035.doi:10.1128/AAC.00440-16.
APA：
Hua Yu,Fen Qu,Bin Shan,Bin Huang,Wei Jia...&Liang Chen.(2016).Detection of the mcr-1 Colistin Resistance Gene in Carbapenem-Resistant Enterobacteriaceae from Different Hospitals in China.ANTIMICROBIAL AGENTS AND CHEMOTHERAPY,60,(8)
MLA：
Hua Yu,et al."Detection of the mcr-1 Colistin Resistance Gene in Carbapenem-Resistant Enterobacteriaceae from Different Hospitals in China".ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 60..8(2016):5033-5035
医学