机构:[1]Department of Ophthalmology, the First People’s Hospital of Kunming City, Kunming, China[2]Department of Ophthalmology, the First Affiliated Hospital of Kunming Medical University, Kunming, China外科科室眼科昆明医科大学附属第一医院[3]Kunming Medical University, Kunming, China[4]State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China[5]School of Public Health, Medical College of Soochow University, Suzhou, China.
Purpose:To determine the 5-year cumulative incidence of pterygium and its associated predictors in the Bai Chinese population in a rural community.Methods:This population-based study included 2133 subjects aged 50 years or older in 2010 and was repeated in 2015 with 1520 subjects (71.3%) participating in the follow-up examination. Participants with pterygium in either eye in 2010 were excluded from the analysis related to incidence. Anterior segment examination was performed without pupil dilation using a slit lamp, and pterygium was defined as a raised fleshy triangular fibrovascular tissue growth of the conjunctiva encroaching onto the clear cornea.Results:The 5-year cumulative incidence of pterygium was 6.8% [95% confidence interval (CI), 5.2-8.4] and was significantly higher in women compared with men (8.8% vs. 3.8%; P = 0.003). The age-specific incidence was 7.7%, 6.5%, and 5.6% in those aged 50-59, 60-69, 70 years, or older at the baseline, respectively. Outdoor occupation was the only predictor, which remained to be significantly associated with a higher incidence of pterygium in multivariate analysis (odds ratio = 2.52, 95% CI, 1.27-4.95). The predictive effect of outdoor occupation on incident pterygium was moderate with an area under the curve in the receiver operating characteristic analysis of 0.59 (95% CI, 0.53-0.66).Conclusions:The incidence of pterygium in this rural cohort was higher compared to a previous report in Chinese in urban areas. The findings are important for health policy makers to project future burden of pterygium and make proper decisions on health resource allocation.
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81460085, 81160121, 81371016]
第一作者机构:[1]Department of Ophthalmology, the First People’s Hospital of Kunming City, Kunming, China
共同第一作者:
通讯作者:
通讯机构:[*1]School of Public Health, Medical College of Soochow University, 199 Ren Ai Rd, Suzhou 215123, China
推荐引用方式(GB/T 7714):
Li Lan,Zhong Hua,Tian Ermiao,et al.Five-Year Incidence and Predictors for Pterygium in a Rural Community in China: The Yunnan Minority Eye Study[J].CORNEA.2015,34(12):1564-1568.doi:10.1097/ICO.0000000000000637.
APA:
Li, Lan,Zhong, Hua,Tian, Ermiao,Yu, Minbin,Yuan, Yuansheng...&Pan, Chen-Wei.(2015).Five-Year Incidence and Predictors for Pterygium in a Rural Community in China: The Yunnan Minority Eye Study.CORNEA,34,(12)
MLA:
Li, Lan,et al."Five-Year Incidence and Predictors for Pterygium in a Rural Community in China: The Yunnan Minority Eye Study".CORNEA 34..12(2015):1564-1568