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Clinical effect of cardiac shock wave therapy on patients with ischaemic heart disease: a systematic review and meta-analysis

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机构: [1]Yunnan Provincial Cardiovascular Institute, [2]Department of Cardiology, 1st Affiliated Hospital of Kunming Medical University, [3]Department of Clinical Laboratory, 1st Affiliated Hospital of Kunming Medical University, Kunming, China
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关键词: Angina pectoris cardiac shock wave ischaemic heart disease

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Background After several years of study, CSWT has been initially applied to IHD treatment, but the actual effectiveness has never been well evaluated with a meta-analysis. Methods MEDLINE, EMBASE, Science Direct, Cochrane Controlled Trials Register database and Chinese database were searched. The randomized controlled trials, and single-arm and cohort study related to in patients with IHD undergoing CSWT were included and 14 articles were finally analysed. The data related to the study design, patient characteristics and outcomes were extracted. All the selected data were calculated with random-effects models in weighted mean differences, and heterogeneity was carefully evaluated as well. Results (i) Cardiac shock wave therapy improves the angina pectoris symptom (including the decrease of Canadian Cardiovascular Society class [-0.86 (-1.12, -0.65), P < 0.00001], nitroglycerin dosage (times/weeks) [-0.71 (-1.08, -0.33), P = 0.0002] and a increase of Seattle Angina Questionnaire score [5.64 (3.12, 8.15), P < 0.0001)]); (ii) CSWT leads to a reduce in heart failure (including a reduction of New York Heart Association functional class [-0.49 (-0.62, -0.37), P < 0.00001], a stable rise in 6-min walking distance [68.38 (39.70, 97.05), P < 0.00001] and a growth in left ventricular ejection fraction with echocardiography screening [6.73 (4.67, 8.80), P < 0.00001]); (iii) CSWT improves myocardial viability within improving in total score of perfusion imaging [-5.19 (-8.08, -2.30), P = 0.0004] and total score of metabolism imaging [-5.33 (-7.77, -2.90), P < 0.0001]. Conclusions The meta-analysis suggests that CSWT may offer beneficial effects to patients with IHD, although there was significant heterogeneity across the studies.

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出版当年[2016]版:
大类 | 3 区 医学
小类 | 3 区 医学:内科 3 区 医学:研究与实验
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 医学:内科 3 区 医学:研究与实验
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出版当年[2015]版:
Q1 MEDICINE, GENERAL & INTERNAL Q2 MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版:
Q1 MEDICINE, GENERAL & INTERNAL Q2 MEDICINE, RESEARCH & EXPERIMENTAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2015版] 出版当年五年平均 出版前一年[2014版] 出版后一年[2016版]

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第一作者机构: [1]Yunnan Provincial Cardiovascular Institute, [2]Department of Cardiology, 1st Affiliated Hospital of Kunming Medical University,
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通讯机构: [1]Yunnan Provincial Cardiovascular Institute, [2]Department of Cardiology, 1st Affiliated Hospital of Kunming Medical University, [*1]Department of Cardiology, 1st Affiliated Hospital of Kunming Medical University, No. 295, Xichang Road, Kunming, Yunnan 650032, China
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