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Phenylethanoid and secoiridoid glycosides from the leaves of Ligustrum purpurascens

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机构: [1]Department of Pharmacy, School of Medicine, Shenzhen University, Shenzhen 518060, PR China [2]JNU-HKUST Joint Laboratory for Neuroscience & Innovative Drug Research, Jinan University, Guangzhou 510632, PR Chin [3]The First Affiliated Hospital of Kunming Medical University, Kunming 650032, PR China
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关键词: Ligustrum purpurascens Oleaceae Phenylethanoid glycoside Secoiridoid glycoside IFN-gamma

摘要:
A new phenylethanoid glycoside (2) and a new secoiridoid glycoside (16) were isolated from the leaves of Ligustrum purpurascens together with fourteen known compounds (1 and 3-15). The structures of the new compounds were determined by spectroscopic analyses (UV, IR, HR-ESI-MS, 1D, and 2D NMR). The absolute configuration of 16 was further determined by CD analysis. All phenylethanoid glycosides were prepared and their up-regulation of IFN-gamma production in mouse splenic lymphocytes was evaluated. Compounds 1, 5, 6, 10, 11, 13 and 15 exhibited potent stimulatory effect on IFN-gamma secretion. (C) 2015 Published by Elsevier B.V. on behalf of Phytochemical Society of Europe.

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出版当年[2016]版:
大类 | 4 区 生物
小类 | 4 区 生化与分子生物学 4 区 植物科学
最新[2023]版:
大类 | 4 区 生物学
小类 | 4 区 药物化学 4 区 植物科学
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出版当年[2015]版:
Q2 PLANT SCIENCES Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
最新[2023]版:
Q3 PLANT SCIENCES Q4 CHEMISTRY, MEDICINAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2015版] 出版当年五年平均 出版前一年[2014版] 出版后一年[2016版]

第一作者:
第一作者机构: [1]Department of Pharmacy, School of Medicine, Shenzhen University, Shenzhen 518060, PR China [2]JNU-HKUST Joint Laboratory for Neuroscience & Innovative Drug Research, Jinan University, Guangzhou 510632, PR Chin
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通讯机构: [*1]Department of Pharmacy, School of Medicine,Shenzhen University, Shenzhen 518060, PR China.
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