机构：[1]Department of Nephrology, State key Laboratory of Kidney Disease, Chinese PLA General Hospital, Beijing 100853, China[2]Nephrology Institute of the Chinese People’s Liberation Army, Chinese People’s Liberation Army Key Laboratory of Nephrology, Beijing 100853, China[3]Department of Nephrology, West China Hospital of Sichuan University, Chengdu, Sichuan 610041, China四川大学华西医院[4]Department of Nephrology, First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310003, China内科系统肾脏病中心浙江大学医学院附属第一医院[5]Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai 200032, China[6]Department of Nephrology, First Affliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510080, China内科科室肾内科中山大学附属第一医院[7]Department of Nephrology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, China内科科室肾内科大连医科大学附属第一医院[8]Department of Nephrology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830054, China[9]Department of Nephrology, First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China[10]Department of Nephrology, First Affliated Hospital of China Medical University, Shenyang, Liaoning 110001, China[11]Department of Nephrology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China[12]Department of Nephrology, Second Xiangya Hospital, Central South University, Changsha, Hunan 410000, China[13]Department of Nephrology, First Affiliated Hospital of Medical College, Xi’an Jiaotong University, Xi’an, Shaanxi 710061, China[14]Department of Nephrology, First Affiliated Hospital of Nanjing Medical University江苏省人民医院[15]Department of Nephrology, Sichuan Provincial People’s Hospital, Chengdu, Sichuan 610072, China四川省人民医院[16]Department of Nephrology, Guangdong Provincial People’s Hospital, Guangzhou, Guangdong 510030, China内科科室肾内科广东省人民医院[17]Department of Nephrology, Affliated Xiehe Hospital, Tongji Medical College, Huazhong Science and Technology University, Wuhan, Hubei 430022, China[18]Department of Nephrology, Daping Hospital, Third Military Medical University, Chongqing 400042, China[19]Department of Nephrology, People’s Hospital of Wuhan University,Wuhan, Hubei 430060, China[20]Department of Nephrology, China-Japan Friendship Hospital, Beijing 100029, China[21]Department of Nephrology, Bethune International Peace Hospital of the Chinese People’s Liberation Army, Shijiazhuang, Hebei 050082, China[22]Department of Nephrology, Second Hospital of Jilin University, Changchun, Jilin 130041, China[23]Department of Nephrology, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai 200025, China[24]Department of Nephrology, First Affiliated Hospital of Wenzhou Medical College, Wenzhou, Zhejiang 325000, China[25]Department of Nephrology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China[26]Department of Nephrology, Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116023, China[27]Department of Nephrology, Huashan Hospital, Fudan University, Department of Nephrology, The Fifth People’s Hospital of Shanghai, Fudan University, Shanghai 200240, China[28]Department of Nephrology, First Affiliated Hospital of Kunming Medical College, Kunming, Yunnan 650032, China内科科室肾脏内科昆明医科大学附属第一医院[29]Department of Nephrology, First People’s Hospital of Yunnan Province, Kunming, Yunnan 650034, China内科科室肾脏内科昆明医科大学附属第一医院云南省第一人民医院[30]Department of Nephrology, General Hospital of Tianjin Medical University, Tianjin 300052, China (Lin S)云南省第一人民医院[31]Department of Nephrology, Affliated Hospital of Ningxia Medical University, Yinchuan, Ningxia 750004, China[32]Department of Nephrology, Neimenggu Autonomous Region Hospital, Hohhot, Inner Mongolia 010017, China[33]Department of Nephrology, Affiliated Hospital of Zunyi Medical College, Zunyi, Guizhou 563000, China[34]Department of Nephrology, First Affliated Hospital of the Medical College of Shihezi University, Shihezi, Xinjiang 832008, China[35]Department of Nephrology, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, China[36]Department of Nephrology, First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350005, China[37]Department of Nephrology, Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai 200233, China[38]Department of Nephrology, People’s Hospital of Tibet Autonomous Region, Lhasa, Tibet 850000, China[39]Department of Nephrology, Lanzhou General Hospital, Lanzhou Command of Chinese People’s Liberation Army, Lanzhou, Gansu 730050, China[40]Department of Nephrology, Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230601, China[41]Department of Nephrology, Affliated Hospital of Medical College, Qingdao University, Qingdao, Shandong 266003, China[42]Department of Nephrology, First Affiliated Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China[43]Department of Nephrology, Zhongda Hospital of Southeast University, Nanjing, Jiangsu 210009, China[44]Department of Nephrology, Second Affiliated Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, China[45]Department of Nephrology, Shandong Provincial Hospital, Jinan, Shandong 250021, China[46]Department of Nephrology, Shanghai People’s Liberation Army 85 Hospital, Shanghai 365326, China[47]Department of Nephrology, Second Hospital of Lanzhou University, Lanzhou, Gansu730030, China[48]Department of Nephrology, Third Affliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, China[49]Department of Nephrology, Henan Provincial People’s Hospital, Zhengzhou, Henan 450000, China中山大学附属第三医院[50]Department of Nephrology, Affliated Hospital of Qinghai University, Xining, Qinghai 810001, China[51]Department of Nephrology, Research Institute of Nephrology, Nanjing General Hospital of Nanjing Command, Nanjing, Jiangsu 210002, China[52]Department of Nephrology, Shanghai Jiao Tong University Affliated First People's Hospital, Shanghai 200240, China[53]Department of Nephrology, Xijing Hospital, Fourth Military Medical University, Xi’an, Shaanxi 710032, China[54]Department of Nephrology, Second Affliated Hospital, Chongqing Medical University, Chongqing 400010, China[55]Department of Nephrology, General Hospital of Navy, Beijing 100048, China[56]Department of Nephrology, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, China[57]Department of Nephrology, First People’s Hospital of Qinghai Province, Xining, Qinghai 810000, China[58]Department of Nephrology, Guangxi Zhuang Autonomous Region People’s Hospital, Nanning, Guangxi 530021, China[59]Department of Nephrology, Second Hospital of Shandong University, Jinan, Shandong 250033, China[60]Department of Nephrology, Second Hospital of Tianjin Medical University, Tianjin 300211, China[61]Department of Nephrology, Affiliated Hospital of Hainan Medical College, Haikou, Hainan 570102, China
Background Data on the epidemiology of hypertension in Chinese non-dialysis chronic kidney disease (CKD) patients are limited. The aim of the present study was to investigate the prevalence, awareness, treatment, and control of hypertension in the non-dialysis CKD patients through a nationwide, multicenter study in China. Methods The survey was performed in 61 tertiary hospitals in 31 provinces, municipalities, and autonomous regions in China (except Hong Kong, Macao, and Taiwan). Trained physicians collected demographic and clinical data and measured blood pressure (BP) using a standardized protocol. Hypertension was defned as systolic BP >= 140 mmHg and/or diastolic BP >= 90mmHg, and/or use of antihypertensive medications. BP<140/90 mmHg and <130/80 mmHg were used as the 2 thresholds of hypertension control. In multivariate logistic regression with adjustment for sex and age, we analyzed the association between CKD stages and uncontrolled hypertension in non-dialysis CKD patients. Results The analysis included 8927 non-dialysis CKD patients. The prevalence, awareness, and treatment of hypertension in non-dialysis CKD patients were 67.3%, 85.8%, and 81.0%, respectively. Of hypertensive CKD patients, 33.1% and 14.1% had controlled BP to <140/90 mmHg and <130/80 mmHg, respectively. With successive CKD stages, the prevalence of hypertension in non-dialysis CKD patients increased, but the control of hypertension decreased (P<0.001). When the threshold of BP <130/80 mmHg was considered, the risk of uncontrolled hypertension in CKD 2,3a, 3b, 4, and 5 stages increased 1.3, 1.4, 1.4, 2.5, and 4.0 times compared with CKD 1 stage, respectively (P<0.05). Using the threshold of <140/90 mmHg, the risk of uncontrolled hypertension increased in advanced stages (P<0.05). Conclusions The prevalence of hypertension Chinese non-dialysis CKD patients was high, and the hypertension control was suboptimal. With successive CKD stages, the risk of uncontrolled hypertension increased.
基金：
National Key Technology RD ProgramNational Key Technology R&D Program [2011BAI10B08]; State Key Development Program for Basic Research of ChinaState Key Development Program for Basic Research of China [2013CB530800]; Health Industry Scientific Research Special Project [20100210]; Clinical Medicine's Special Purpose Fund of the Chinese Medical Association [12020390329]
第一作者机构：[1]Department of Nephrology, State key Laboratory of Kidney Disease, Chinese PLA General Hospital, Beijing 100853, China
共同第一作者：
通讯作者：
通讯机构：[*1]Department of Nephrology, State key Laboratory of Kidney Disease, Nephrology Institute of the Chinese People’s Liberation Army, Chinese People’s Liberation Army Key Laboratory of Nephrology, Chinese People’s Liberation Army General Hospital, Beijing 100853, China
推荐引用方式(GB/T 7714)：
ZHENG Ying,CAI Guang-yan,CHEN Xiang-mei,et al.Prevalence, awareness, treatment, and control of hypertension in the non-dialysis chronic kidney disease patients[J].CHINESE MEDICAL JOURNAL.2013,126(12):2276-2280.doi:10.3760/cmaj.issn.0366-6999.20130835.
APA：
ZHENG Ying,CAI Guang-yan,CHEN Xiang-mei,FU Ping,CHEN Jiang-hua...&Prevalence,Awareness and Treatment Rates in Chronic Kidney Disease Patients with Hypertension in China.(2013).Prevalence, awareness, treatment, and control of hypertension in the non-dialysis chronic kidney disease patients.CHINESE MEDICAL JOURNAL,126,(12)
MLA：
ZHENG Ying,et al."Prevalence, awareness, treatment, and control of hypertension in the non-dialysis chronic kidney disease patients".CHINESE MEDICAL JOURNAL 126..12(2013):2276-2280
