机构:[a]Department of Radiology, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo 113-8655, Japan,[b]Department of Radiology, Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo 108-8639, Japan,[c]Department of Radiology, First Affiliated Hospital, Kunming Medical University, Kunming city 650032, China医技科室医学影像中心放射科昆明医科大学附属第一医院
Patients with hepatocellular carcinoma (HCC) complicated by portal vein tumor thrombus (PVTT) have an extremely poor prognosis. It is important to select adequate therapeutic options based on reliable prognostic factors using imaging studies and clinical data. Prognostic factors were analyzed in patients with HCC with PVTT in the first branch or main trunk of the portal vein. From 2000 to 2007, 107 consecutive patients with HCC with PVTT in the major portal vein were reviewed, and diagnostic images and clinical characteristics were retrospectively observed. Thirty-eight possible prognostic factors for survival were analyzed by the log-rank test and multivariate analysis using Cox's proportional hazards model. Median overall survival was 14 months following PVTT diagnosis. Survival rates at 6 months, 1, 2, and 3 years were 72.1%, 52.6%, 32.6%, and 29.6%, respectively. Independent prognostic factors for longer survival included: patient age <65 years, Child-Pugh classification A/B, PVTT treatment, accumulation of Lipiodol in the PVTT after TACE, initial radical treatment for HCC, HCC located in a single lobe of the liver, and no invasion of HCC to the hepatic vein or bile duct. Survival was associated with liver function, tumor extension, and treatment for HCC and PVTT.
第一作者机构:[a]Department of Radiology, Graduate School of Medicine, University of Tokyo, Bunkyo-ku, Tokyo 113-8655, Japan,[c]Department of Radiology, First Affiliated Hospital, Kunming Medical University, Kunming city 650032, China
通讯作者:
推荐引用方式(GB/T 7714):
Lizhong Jia,Shigeru Kiryu,Takeyuki Watadani,et al.Prognosis of Hepatocellular Carcinoma with Portal Vein Tumor Thrombus: Assessment Based on Clinical and Computer Tomography Characteristics[J].ACTA MEDICA OKAYAMA.2012,66(2):131-141.
APA:
Lizhong Jia,Shigeru Kiryu,Takeyuki Watadani,Hiroyuki Akai,Hideomi Yamashita...&Kuni Ohtomo.(2012).Prognosis of Hepatocellular Carcinoma with Portal Vein Tumor Thrombus: Assessment Based on Clinical and Computer Tomography Characteristics.ACTA MEDICA OKAYAMA,66,(2)
MLA:
Lizhong Jia,et al."Prognosis of Hepatocellular Carcinoma with Portal Vein Tumor Thrombus: Assessment Based on Clinical and Computer Tomography Characteristics".ACTA MEDICA OKAYAMA 66..2(2012):131-141