个人科研网厅 | | 帮助
高级检索
当前位置： 首页 > 详情页

The association between plasma HMGB1 and sRAGE and clinical outcome in intracerebral hemorrhage

| 导出 | |

文献详情

资源类型：
WOS体系：
Pubmed体系：

收录情况： ◇ SCIE

作者：
Chunyan Lei[1,2] ; Jia Geng[1] ; Lianmei Zhong[1] ;
机构： [1]Department of Neurology, First Affiliated Hospital of Kunming Medical University, Yunnan Province, China [2]Department of Neurology, First Affiliated Hospital of Kunming Medical University, No. 295 Xi Chang Lu, Kunming 650032, Yunnan Province, PR China
出处：
DOI： 10.1016/j.jneuroim.2020.577266
ISSN：

关键词： Clinical outcome HMGB1 Intracerebral hemorrhage sRAGE

摘要：
High-mobility group box 1 (HMGB1) and advanced glycation end-products (RAGE) are potential mediators of inflammation. We investigate the association between levels of HMGB1 and soluble RAGE (sRAGE) following intracerebral hemorrhage (ICH) and the severity of ICH. There was a significant trend towards higher poor functional outcome rate with increasing HMGB1 and sRAGE tercile. The correlation analysis indicated that the levels of HMGB1and sRAGE were positively correlated with hematoma volume. The receiver operating curve (ROC) was 0.718 for HMGB1 and 0.631 for sRAGE to poor functional outcome. HMGB1 and sRAGE quantification provides more accurate prognostic information after ICH. © 2020

基金：
This study was supported by a grant from the National Natural Science Foundation of China (grant no. 81701173 ) and Applied Basic Research Joint fund Project of Yunnan Province (grant no. 2018FE001(-141) ).
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2021]版：
大类 | 3 区 医学
小类 | 3 区 神经科学 4 区 免疫学
最新[2023]版：
大类 | 4 区 医学
小类 | 4 区 免疫学 4 区 神经科学
JCR分区：
出版当年[2020]版：
Q3 IMMUNOLOGY Q3 NEUROSCIENCES
最新[2023]版：
Q2 NEUROSCIENCES Q3 IMMUNOLOGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2020版] 出版当年五年平均 出版前一年[2019版] 出版后一年[2021版]

第一作者：
第一作者机构： [1]Department of Neurology, First Affiliated Hospital of Kunming Medical University, Yunnan Province, China [2]Department of Neurology, First Affiliated Hospital of Kunming Medical University, No. 295 Xi Chang Lu, Kunming 650032, Yunnan Province, PR China
通讯作者：
通讯机构： [2]Department of Neurology, First Affiliated Hospital of Kunming Medical University, No. 295 Xi Chang Lu, Kunming 650032, Yunnan Province, PR China
推荐引用方式(GB/T 7714)：
Chunyan Lei,Jia Geng,Lianmei Zhong.The association between plasma HMGB1 and sRAGE and clinical outcome in intracerebral hemorrhage[J].JOURNAL OF NEUROIMMUNOLOGY.2020,345:doi:10.1016/j.jneuroim.2020.577266.
APA：
Chunyan Lei,Jia Geng&Lianmei Zhong.(2020).The association between plasma HMGB1 and sRAGE and clinical outcome in intracerebral hemorrhage.JOURNAL OF NEUROIMMUNOLOGY,345,
MLA：
Chunyan Lei,et al."The association between plasma HMGB1 and sRAGE and clinical outcome in intracerebral hemorrhage".JOURNAL OF NEUROIMMUNOLOGY 345.(2020)

相关文献

[1]The association between TLR2/4 and clinical outcome in intracerebral hemorrhage [2]HMGB1/TLR4 induces autophagy and promotes neuroinflammation after intracerebral hemorrhage [3]Different criteria for defining "spot sign" in intracerebral hemorrhage show different abilities to predict hematoma expansion and clinical outcomes: a systematic review and meta-analysis. [4]HMGB1/TLR4 axis promotes pyroptosis after ICH by activating the NLRP3 inflammasome [5]Cardiac troponin and cerebral herniation in acute intracerebral hemorrhage [6]Pre-Intracerebral Hemorrhage and In-Hospital Statin Use in Intracerebral Hemorrhage: A Systematic Review and Meta-analysis [7]Analgesia-first Minimal Sedation for Spontaneous Intracerebral Hemorrhage Early Antihypertensive Treatment (ASSICHH) [8]Sex-Specific Differences in Clinical Characteristics and Outcomes Among Patients with Vascular Abnormality-Related Intracerebral Hemorrhage [9]Xenon as a therapy in experimental intracerebral hemorrhage [10]Characterization of Axon Damage, Neurological Deficits, and Histopathology in Two Experimental Models of Intracerebral Hemorrhage

资源点击量：52537 今日访问量：0 总访问量：1562 更新日期：2024-09-01 建议使用谷歌、火狐浏览器 常见问题

版权所有©2020 昆明医科大学第一附属医院 技术支持：重庆聚合科技有限公司 地址：云南省昆明市西昌路295号(650032)