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2 cases of multiple myeloma onset from coagulation disorder and literature review

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机构: [1]Department of Hematology, First Affiliated Hospital of Kunming Medical University, Kunming 650032, Yunnan, China [2]Hematology Research Center of Yunnan Province, Kunming 650032, Yunnan, China [3]Department of Oncology, First Affiliated Hospital of Kunming Medical University, Kunming 650032, Yunnan, China
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关键词: Coagulation disorder IgG type Multiple myeloma Treatment

摘要:
This article retrospectively analyzed 2 cases of multiple myeloma (MM) with onset from coagulation disorder, and reviewed the similar cases in literatures. 2 patients all exhibited skin and mucosal bleeding as the first symptom, among who one case exhibited extended prothrombin time (PT) and thrombin time, increased D-dimer quantitation, reduced clotting factor XII, while the other case exhibited extended PT and activated partial thrombo-plastin time. Both cases had no associated symptom such as pain, fever, etc., and were diagnosed as MM IgG type. Combining the retrieved similar cases, it is found that MM patients with onset from coagulation disorder all belong to IgG type, and the types of the coagulation abnormality are diverse, with no special rule. The relationship between MM and coagulation disorder are complex, and the current therapeutic strategy still mainly depends on treating the basic diseases. © 2017, E-Century Publishing Corporation. All rights reserved.

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中科院(CAS)分区:
出版当年[2018]版:
大类 | 4 区 医学
小类 | 4 区 医学:研究与实验
最新[2023]版:
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出版当年[2017]版:
Q4 MEDICINE, RESEARCH & EXPERIMENTAL
最新[2023]版:
Q4 MEDICINE, RESEARCH & EXPERIMENTAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2017版] 出版当年五年平均 出版前一年[2016版] 出版后一年[2018版]

第一作者:
第一作者机构: [1]Department of Hematology, First Affiliated Hospital of Kunming Medical University, Kunming 650032, Yunnan, China [2]Hematology Research Center of Yunnan Province, Kunming 650032, Yunnan, China
通讯作者:
通讯机构: [1]Department of Hematology, First Affiliated Hospital of Kunming Medical University, Kunming 650032, Yunnan, China [2]Hematology Research Center of Yunnan Province, Kunming 650032, Yunnan, China [*1]Department of Hematology, First Affiliated Hospital of Kunming Medical University, No. 295 Xichang Road, Kunming 650032, Yunnan, China
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