机构:[a]Department of Pediatrics, The First Affiliated Hospital, Kunming Medical University, Kunming, Yunnan Province 650032, China内科科室儿科昆明医科大学附属第一医院[b]Department of Pathology, The First Affiliated Hospital, Kunming Medical University, Kunming, Yunnan Province 650032, China医技科室病理科昆明医科大学附属第一医院
METHODS: Eighty-two male SD rats were randomly divided into a normal group, a model group and three intervention groups including Smecta group, mesalazine group, and mesalazine plus Smecta group. Ulcerative colitis (UC) was induced in rats by the TNBS/ethanol method. The model group was daily treated with normal saline, and the intervention groups were intragastrically treated with Smecta, mesalazine, mesalazine plus Smecta, respectively. Rats were killed on days 5 and 12 after treatment to collect colon specimens. Terminal-deoxynucleoitidyl transferase mediated nick end labeling (TUNEL) method was used to assay intestinal cell apoptosis rate.
语种:
中文
第一作者:
第一作者机构:[a]Department of Pediatrics, The First Affiliated Hospital, Kunming Medical University, Kunming, Yunnan Province 650032, China
通讯作者:
推荐引用方式(GB/T 7714):
Yuan M.-M,Xiong J.-J,Zhao C,等.Effect of montmorillonite powder and mesalazine on intestinal epithelial cell apoptosis in rats with ulcerative colitis[J].World Chinese Journal of Digestology.2014,22(26):