机构：[1]Department of Hematology, The First Affiliated Hospital of Kunming Medical University, Yunnan Province, China内科科室血液内科昆明医科大学附属第一医院
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摘要：
The promyelocytic leukemia protein (PML), encoded by PML gene, plays a tumor suppressor in acute promyelocytic leukemia and other hematologic malignancies. Recent evidence indicates that PML involves in regulating multiple cell biological function, regulates self-renewal and maintains stable function in stem cell/cancer stem cell of multiple tissues, leading to drug resistance of cancer. This review summarizes the latest research advances about the relationship and therapeutic options between PML and cancer stem cell of hematologic neoplasms, aiming to propose a new avenue for blood cancer treatment.
语种：
中文
第一作者：
第一作者机构：[1]Department of Hematology, The First Affiliated Hospital of Kunming Medical University, Yunnan Province, China
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推荐引用方式(GB/T 7714)：
Zhao H.Y,Li H.M.[Progress of study on PML in cancer stem cell of hematologic malignancies].[J].Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology.2013,21(3):
