机构：[a]ICU, Hospital of Chinese Traditional Medicine of Guangdong Province, Fu Shan 528000, China重症医学专科(ICU)广东省中医院[b]Depatment of Anesthesiology, Affiliated Hospital, Tongji Medical University, Wuhan 430030, China[c]ICU, First Affiliated Hospital of Kunming Medical College, Kunming 650032, China内科科室外科科室干疗科3号楼重症监护病房（ICU）重症医学科昆明医科大学附属第一医院[d]Depatment of Pharmacology, School of Basic Medical College, Tongji Medical University, Wuhan 430030, China
Objective: To evaluate the effect of Rg 1 (purified saponin of Panax notoginseng) on L-Ca 2+ channel of guinea pig ventricular myocytes. Method: The whole-cell patch clamp recording technique. Result: When the holding potential was kept, at-40 mV, and the cell was depolarized to + 40mV for 150 ms at a frequency of 0.5Hz. Rg 1 10 μmol·L -1 and 30μmol· -1 could not reduce Bay K 8644 and nifedipine-sensitive L-type Ca 2+ inward current (P>0.05, n = 5). Conclusion: Rg 1 should not be a Ca 2+ channel antagonist.
语种：
中文
第一作者：
第一作者机构：[a]ICU, Hospital of Chinese Traditional Medicine of Guangdong Province, Fu Shan 528000, China
推荐引用方式(GB/T 7714)：
Zhang B,Jin S,Kuang X,等.Effects of Rg 1 on calcium channel of guinea pig ventricular myocytes[J].Zhongguo Zhongyao Zazhi.1999,24(10):
