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Clinical characteristics, rates of blindness, and geographic features of primary angle-closure disease in hospitals of the Chinese Glaucoma Study Consortium.

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机构: [1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China [2]Beijing Ophthalmology and Visual Science Key Lab. [2]Beijing Institute of Ophthalmology. [3]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China. [4]Beijing Clinical Service Center. [5]Handan City Eye Hospital. [6]The First Affiliated Hospital of Harbin Medical University. [7]Department of Ophthalmology, Ning Xia Eye Hospital, People's Hospital of Ningxia Hui Autonomous Region. [8]The Second Xiangya Hospital of Central South University. [9]Xi'an Fourth Hospital. [10]Tang Shan City Eye Hospital. [11]The First Hospital of Shijiazhuang City. [12]Baotou Chaoju Ophthalmic Hospital. [13]Tianjin Eye Hospital. [14]Liaocheng People's Hospital. [15]Yuncheng City Eye Hospital. [16]Lanzhou University Second Hospital. [17]Eye Hospital, China Academy of Chinese Medical Sciences. [18]No. 1 Hospital of Xi 'An City. [19]West China Hospital, Sichuan University. [20]The Second Hospital of Heibei Medical University. [21]The Second People's Hospital of Jinan. [22]Dongguan People's Hospital. [23]The Eye Hospital of Wenzhou Medical University. [24]The 4th Affiliated Hospital of China Medical University, the Eye Hospital of China Medical University. [25]Xuanwu Hospital, Capital Medical University. [26]The First Affiliated Hospital of Kunming Medical University. [27]The First People's Hospital of Xuzhou. [28]Wuhan Aier Eye Hospital. [29]FuShun Eye Hospital. [30]The Affiliated Hospital of Southwest Medical University. [31]The Third Medical Center of Chinese PLA General Hospital. [32]The Second Hospital of Jilin University. [33]Jinzhou Central Hospital. [34]Zibo Central Hospital. [35]Baoji People's Hospital. [36]Shanxi Eye Hospital. [37]ShiYan People's Hospital. [38]Yichang Central Hospital. [39]The First People's Hospital of Foshan. [40]Habin Ophthalmology Hospital. [41]Liuzhou People's Hospital. [42]ChengDu First People's Hospital. [43]Shenzhen Eye Hospital. [44]Taihe Hospital, Hubei University of Medicine. [45]Huashan Hospital of Fudan University. [46]The First Affiliated Hospital of Dalian Medical University. [47]The First Affiliated Hospital of Fujian Medical University. [48]Hebei Eye Hospital. [49]Mian Yang Central Hospital. [50]The Second Hospital of Dalian Medical University. [51]Wuxi NO.2 People's Hospital. [52]Taian Central Hospital. [53]Eye Hospital of NanYang City. [54]Palo Alto Medical Foundation. [55]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China [57]Beijing Ophthalmology and Visual Science Key Lab [58]Beijing Institute of Ophthalmology. [56]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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To analyze the rates of blindness with the demographics and clinical characteristics of patients with primary angle-closure disease (PACD) to provide a comprehensive epidemiologic reference in China. A retrospective analysis was conducted in the Chinese Glaucoma Study Consortium database, which is a national multicenter glaucoma research alliance of 111 hospitals participating between December 21, 2015 and September 9, 2018. The diagnosis of PACD was made by qualified physicians through examination. Comparison of sex, age, family history, subtypes of PACD, and blindness were analyzed. A total of 5762 glaucoma patients were included, of which 4588 (79.6%) had PACD. Of PACD patients, 72.1% were female with the sex ratio (F/M) of 2.6, and the average age of patients was 63.8±9.3 years with the majority between 60 and 70 years. Additionally, 30% of these patients had low vision in one eye, 8.8% had low vision in both eyes, 1.7% had blindness in one eye, and 0.3% had blindness in both eyes. There were statistical differences with regards to age between male and female patients with PACD, with male patients being older on average. Primary angle-closure glaucoma was more commonly diagnosed in males (60%) compared to females (35.9%), whereas acute primary angle closure (APAC) was more commonly diagnosed in females (54.3%) compared to males (37.7%). The visual acuity in APAC patients was lower and the rate of low vision and blindness was higher than other subtypes. PACD was the major type of glaucoma in Chinese hospitals. There were more female patients with PACD, mostly between 60 and 70 years old, with higher rates of APAC in women. APAC resulted in the worst visual outcomes of all PACD subtypes. Copyright © 2020. Published by Elsevier Inc.

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出版当年[2022]版:
大类 | 4 区 医学
小类 | 4 区 眼科学
最新[2023]版:
大类 | 4 区 医学
小类 | 3 区 眼科学
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出版当年[2021]版:
Q3 OPHTHALMOLOGY
最新[2023]版:
Q1 OPHTHALMOLOGY

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第一作者机构: [1]Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China
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