详情页 - 昆明医科大学第一附属医院知识库

当前位置：首页 > 详情页

Generation of a human induced pluripotent stem cell line (SJTUXHi002-A) from an individual with autism spectrum disorder carrying a heterozygous mutation in GRIA2.

123| 认领 | 导出 | 链接全文 |

文献详情

资源类型：

WOS体系：

Pubmed体系：

收录情况： ◇ SCIE ◇ SSCI

作者：

机构： [1]Developmental and Behavioural Pediatric Department & Child Primary Care Department, Brain and Behavioural Research Unit of Shanghai Institute for Pediatric Research and MOE-Shanghai Key Laboratory for Children’s Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China [2]Central Hospital of Jing’An District, Jing’An Branch of Huashan Hospital Affiliated to Fudan University, Shanghai 200040, China [3]Center for Experimental Studies and Research, The First Affiliated Hospital of Kunming Medical University, Kunming 650032, China [4]Department of Child Health Care, Children’s Hospital Affiliated to Zhengzhou University, City Zhengzhou, China

出处：

DOI：

ISSN：

摘要：

Herein, we report the generation of a human induced pluripotent stem cell (iPSC) line from an autism spectrum disorder (ASD) patient carrying the c.1998delT mutation in GRIA2 gene. The generated iPSC line exhibits normal karyotype, pluripotency markers and was able to differentiate into three germ layers. The iPSC line retained the GRIA2 mutation (c.1998delT), which could provide a valuable resource for investing pathogenic mechanisms underlying ASD and facilitating the development of targeted medicine.Copyright © 2022. Published by Elsevier B.V.

基金：

语种：

被引次数：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2023]版：

大类 | 4 区医学

小类 | 4 区生物工程与应用微生物 4 区细胞与组织工程 4 区细胞生物学

最新[2023]版：

大类 | 4 区医学

小类 | 4 区生物工程与应用微生物 4 区细胞与组织工程 4 区细胞生物学

JCR分区：

出版当年[2022]版：

Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Q4 CELL & TISSUE ENGINEERING Q4 CELL BIOLOGY

最新[2023]版：

Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Q4 CELL & TISSUE ENGINEERING Q4 CELL BIOLOGY

影响因子： 0.8 最新[2023版] 1.1 最新五年平均 1.2 出版当年[2022版] 1.5 出版当年五年平均 1.587 出版前一年[2021版] 0.8 出版后一年[2023版]

第一作者：

第一作者机构： [2]Central Hospital of Jing’An District, Jing’An Branch of Huashan Hospital Affiliated to Fudan University, Shanghai 200040, China

共同第一作者：

通讯作者：

推荐引用方式(GB/T 7714)：

APA：

MLA：