研究单位：[1]Shenyang Northern Hospital[2]The Armed Police General Hospital,BeiJing,Beijing,China,100000[3]The Chinese people''s liberation army general hospital affiliated hospitals,BeiJing,Beijing,China,100000[4]Peking University first hospital,Beijing,Beijing,China,100034[5]General Hospital Of The Second Artillery Force of the PLA,BeiJing,Beijing,China,100088[6]The General Hospital of the People''s Liberation Army (PLAGH) ( Hospital 301),BeiJing,Beijing,China,100853[7]The Third Military Medical University, Chongqing Xinqiao Hospital,ChongQing,Chongqing,China,400037[8]Daping Hospital and the Research Institute of Surgery of the Third Military Medical University,ChongQing,Chongqing,China,400042[9]First Hospital of Lanzhou University,LanZhou,Gansu,China,730000[10]Dongguan Kanghua Hospital,DongGuan,Guangdong,China,523080[11]General Hospital of Guangzhou Military Command of PLA,GuangZhou,Guangdong,China,510010[12]The First Affiliated Hospital of Guangzhou Medical College,GuangZhou,Guangdong,China,510120[13]Chinese People''s Liberation Army 252th Hostipal,BaoDing,Hebei,China,610000[14]CanZhou Central Hospital,CangZhou,Hebei,China,610001[15]Shijiazhuang International Peace Hospital,ShiJiaZhuang,Hebei,China,600082[16]The Fourth Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,China,150001[17]The Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,China,150086[18]HeNan Provincial People''s Hospital,ZhengZhou,Henan,China[19]WuHan Asia Heart Hosital,WuHan,Hubei,China,430022[20]WuHan Union Hospital Of China,WuHan,Hubei,China,430022[21]TongJi Medical College HuaZhong University Of Science & Technology,WuHan,Hubei,China,430030[22]Renmin Hospital Of Wuhan University,WuHan,Hubei,China,430060[23]Wuhan General Hospital of Guangzhou Military Area Command of Chinese PLA,WuHan,Hubei,China,430070[24]Nanjing First Hospital,NanJing,Jiangsu,China,210006[25]NanJing Drum Tower Hospital,NanJing,Jiangsu,China,210008[26]FAW subsidiary of the General Hospital of Jilin University (Jilin University, Fourth Hospital),ChangChun,Jilin,China,130011[27]The First Hospital of Jilin University,Changchun,Jilin,China,130021[28]The Second Hospital of Jilin University,Changchun,Jilin,China,130041[29]Changchun Central Hospital,ChangChun,Jilin,China,130051[30]General Hospital of Liaoning Anshan Iron and Steel Group Corporation,AnShan,Liaoning,China,114001[31]Affiliated Zhongshan Hospital of Dalian University,DaLian,Liaoning,China,116001[32]Fushun central hospital,FuShun,Liaoning,China,113006[33]The First Affiliated Hospital of Liaoning Medical College,Jinzhou,Liaoning,China,121001[34]ShenZhou Hopital Of ShenYang Medical College,ShengYang,Liaoning,China,110032[35]PLA 202 Hospital,ShenYang,Liaoning,China,110004[36]Shenyang Nortern Hospital,Shenyang,Liaoning,China,110016[37]Affiliated Hospital of LiaoNing University of Traditional Chinese Medicine,ShenYang,Liaoning,China,110032[38]The Fourth Affiliated Hospital of China Medical University,Shenyang,Liaoning,China,110032[39]The 463th Hospital Of PLA,ShenYang,Liaoning,China,110042[40]Affiliated Hospital of Ningxia Medical College,Yinchuan,Ningxia,China,750004[41]General Hospital of Jinan Military Area Command of Chinese PLA,JiNan,Shandong,China,250031[42]88th Hospital of the Chinese PLA,TaiAn,Shandong,China,271000[43]Ruijin Hospital Affiliated to the Medical College of Shanghai Jiaotong University,ShangHai,Shanghai,China,200025[44]Xijing Hospital of the Fourth Military Medical University,XiAn,Shanxi,China,710032[45]Chengdu Military General Hospital,ChengDu,Sichuan,China,610083[46]PLA 254 Hosipital,TianJin,Tianjin,China,300142[47]Affiliated Hospital Of Medical College Of The Chinese People''s Armed Polic Forces,TianJin,Tianjin,China,300162[48]WuluMuqi General Hospital of PLA Lanzhou Military Area Command,WuLuMuQI,Xinjiang,China,830000[49]The First Affilliated Hospital Of Xinjiang Medical University,Wulumuqi,Xinjiang,China,830054[50]The First Affiliated Hospital of Kunming Medical College,KunMing,Yunnan,China,650031[51]Kunming General Hospital of PLA,KunMing,Yunnan,China,650032[52]The First Affiliated Hospital of Wenzhou Medical College,WenZhou,Zhejiang,China,325000[53]Baotou city central hospital,BaoTou,China,014000[54]Baotou iron and steel group company worker hospital,BaoTou,China,014040
The number of cardiac angiography and percutaneous coronary interventions (PCI) has increased steadily in recent years. This has resulted in the increasing incidence of contrast-induced acute kidney injury (CIAKI). Major risk factors for CIAKI include older age, diabetes mellitus (DM), chronic kidney disease(CKD), the concurrent use of nephrotoxic drugs, hemodynamic instability, etc. Importantly, DM appears to act as a risk multiplier, meaning that in a patient with CKD it amplifies the risk of CIAKI. The aim of this multicenter prospective, randomized, controlled study is to evaluate whether statins treatment during the perioperative period would reduce the risk of CIAKI in a high-risk population of patients with both type 2 diabetes mellitus (T2DM) and CKD undergoing coronary angiography or noncoronary angiography, and evaluate the influence of such potential benefit on short-term outcome.
