研究单位：[1]BeiGene[2]The First Affiliated Hospital of Bengbu Medical College,Bengbu,Anhui,China,233004[3]Anhui Provincial Hospital,Hefei,Anhui,China,230000[4]Peking University Third Hospital,Beijing,Beijing,China,100000[5]Beijing Chao Yang Hospital,Beijing,Beijing,China,100020[6]Xinqiao Hospital Affiliated to the Army Medical University,Chongqing,Chongqing,China,400037[7]Fujian Medical University Union Hospital,Fuzhou,Fujian,China,350001[8]Sun Yat Sen University Cancer Center,Guangzhou,Guangdong,China,510060[9]Guangdong Provincial Peoples Hospital Huifu Branch,Guangzhou,Guangdong,China,510120[10]The Peoples Hospital of Guangxi Zhuang Autonomous Region,Nanning,Guangxi,China,530021[11]Nanyang Central Hospital,Nanyang,Henan,China,473000[12]Henan Cancer Hospital,Zhengzhou,Henan,China,450000[13]Union Hospital of Tongji Medical College, Huazhong University of Science and Technology,Wuhan,Hubei,China,430022[14]Xiangyang Central Hospital,Xiangyang,Hubei,China,441021[15]The Second Xiangya Hospital of Central South University,Changsha,Hunan,China,410011[16]Jiangsu Province Hospital,Nanjing,Jiangsu,China,210029[17]The First Affiliated Hospital of Soochow University,Suzhou,Jiangsu,China,215006[18]Wuxi Peoples Hospital,Wuxi,Jiangsu,China,214023[19]The First Affiliated Hospital of Nanchang University Branch Donghu,Nanchang,Jiangxi,China,330006[20]Jiangxi Province Cancer Hospital,Nanchang,Jiangxi,China,330029[21]The First Hospital of Jilin University,Changchun,Jilin,China,130021[22]Affiliated Zhongshan Hospital of Dalian University,Dalian,Liaoning,China,116001[23]Shandong Cancer Hospital,Jinan,Shandong,China,250117[24]Qingdao Central Hospital,Qingdao,Shandong,China,266031[25]Rui Jin Hospital Shanghai Jiao Tong University School of Medicine,Shanghai,Shanghai,China,200025[26]Shanxi Provincial Cancer Hospital,Taiyuan,Shanxi,China,030013[27]West China Hospital, Sichuan University,Chengdu,Sichuan,China,610041[28]Institute of Hematology and Hospital of Blood Disease,Tianjin,Tianjin,China,300020[29]First Affiliated Hospital of Kunming Medical University,Kunming,Yunnan,China,650032[30]The First Affiliated Hospital, Zhejiang University School of Medicine Branch Yuhang,Hangzhou,Zhejiang,China,311121[31]The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,Zhejiang,China,325000
This study aims to explore the recommended phase 2 dose and evaluate the safety, tolerability and preliminary antitumor activity of BGB-16673 monotherapy at the recommended Phase 2 dose for the selected B-cell malignancy expansion cohorts
