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A Novel Nomogram to Predict the Postoperative Overall Survival in Gastrointestinal Cancer Patients

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多中心研究:
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研究单位: [1]Jinling Hospital Nanjing, Jiangsu, China, 210002 [2]Jiangsu Cancer Institute & Hospital [3]Xijing Hospital [4]Northern Jiangsu Province People's Hospital [5]The Affiliated Hospital of Qingdao University [6]Shanghai 10th People's Hospital [7]West China Hospital [8]First Affiliated Hospital of Kunming Medical University [9]The Second Affiliated Hospital of Harbin Medical University [10]Peking Union Medical College Hospital [11]Chinese PLA General Hospital

关键词: Gastrointestinal Cancer NRS 2002 Postoperative survival Nomogram multicenter study

研究目的:
This multicenter retrospectively observational cohort study was conducted on participants with histologically confirmed gastric and colorectal cancer who underwent radical surgery in 11 medical centers in China from August 1, 2015, to June 31, 2018. Baseline clinicopathologic data and nutritional status assessments including Nutrition Risk Screening 2002 (NRS 2002) score and Patient-generated Subjective Global Assessment (PG-SGA) rating were collected. Variables will be screened using the least absolute shrinkage and selection operator (LASSO) regression model and Cox regression analysis. Internal and external validations will be performed via the receiver operating curve (ROC), the area under the curve (AUC), the concordance index (C-index), calibration plots, decision curve analysis (DCA), and Five folds cross-validation by 200 times.

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