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An Efficacy and Safety Study of Sodium Oligomannate (GV-971) for the Treatment of Alzheimer's Disease

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研究单位: [1]Green Valley (Shanghai) Pharmaceuticals Co., Ltd. [2]Huainan First People's Hospital,Huainan,Anhui,China [3]Beijing Anding Hospital, Capital Medical University,Beijing,Beijing,China [4]Beijing Anzhen Hospital, Capital Medical University,Beijing,Beijing,China [5]Beijing Hospital,Beijing,Beijing,China [6]Beijing Tongren Hospital, Capital Medical University,Beijing,Beijing,China [7]Peking University Shougang Hospital,Beijing,Beijing,China [8]The First Medical Center, Chinese PLA General Hospital,Beijing,Beijing,China [9]Xuanwu Hospital, Capital Medical University,Beijing,Beijing,China [10]The First Affiliated Hopsital of Xiamen University,Xiamen,Fujian,China [11]Guangdong Provincial Hospital of Chinese Medicine,Guangzhou,Guangdong,China [12]The Affiliated Brain Hospital of Guangzhou Medical University,Guangzhou,Guangdong,China [13]The First Affiliated Hopsital of Guangzhou Medical University,Guangzhou,Guangdong,China [14]The Second Affiliated Hopsital of Guangzhou Medical University,Guangzhou,Guangdong,China [15]Peking University Shenzhen Hospital,Shenzhen,Guangdong,China [16]The First People's Hospital of Nanning,Nanning,Guangxi,China [17]Shijiazhuang People's Hospital,Shijiazhuang,Hebei,China [18]The First Hospital of Hebei Medical University,Shijiazhuang,Hebei,China [19]The Second Hopsital of Hebei Medical University,Shijiazhuang,Hebei,China [20]Tangshan Workers' Hospital,Tangshan,Hebei,China [21]The First Affiliated Hopsital of Nanyang Medical College,Nanyang,Henan,China [22]Henan Provincial People's Hospital,Zhengzhou,Henan,China [23]Wuhan Hospital of Traditional Chinese and Western Medicine (Wuhan No.1 Hospital),Wuhan,Hubei,China [24]The Third Xiangya Hospital of Central South University,Changsha,Hunan,China [25]Xiangya Hospital Central South University,Changsha,Hunan,China [26]Chenzhou First People's Hospital,Chenzhou,Hunan,China [27]Yueyang Central Hospital,Yueyang,Hunan,China [28]Huai'an Second People's Hospital,Huai'an,Jiangsu,China [29]Nanjing Brain Hospital,Nanjing,Jiangsu,China [30]Affiliated Hospital of Nantong University,Nantong,Jiangsu,China [31]The Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu,China [32]Yangzhou First People's Hospital,Yangzhou,Jiangsu,China [33]Jiujiang University Affiliated Hospital,Jiujiang,Jiangxi,China [34]The Second Affiliated Hopsital of Nanchang University,Nanchang,Jiangxi,China [35]The First Bethune Hospital of Jilin University,Changchun,Jilin,China [36]Inner Mongolia International Hospital of Mongolian Medicine,Hohhot,Neimenggu,China [37]Qilu Hospital of Shandong University,Jinan,Shandong,China [38]Shandong Provincial Hospital,Jinan,Shandong,China [39]Qilu Hospital of Shandong University (Qingdao),Qingdao,Shandong,China [40]The Affiliated Hospital of Qingdao University,Qingdao,Shandong,China [41]Yantai Yuhuangding Hospital,Yantai,Shandong,China [42]Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine,Shanghai,Shanghai,China [43]The Second Affiliated Hospital of Air Force Medical University (Tangdu Hospital of Air Force Medical University),Xi'an,Shanxi,China [44]Xi'an Mental Health Center,Xi'an,Shanxi,China [45]Xianyang Hospital of Yan'an University,Xianyang,Shanxi,China [46]Hospital of Chengdu University of TCM,Chengdu,Sichuan,China [47]Tianjin People's Hospital,Tianjin,Tianjin,China [48]The Affiliated Hopsital of Inner Mongolia Medical University,Urumqi,Xinjiang,China [49]First Affiliated Hospital of Kunming Medical University,Kunming,Yunnan,China [50]The First Affiliated Hospital Zhejiang University School of Medicine,Hangzhou,Zhejiang,China [51]The Second Hospital of Jiaxing,Jiaxing,Zhejiang,China

研究目的:
The primary purpose of this study is to confirm the clinical efficacy and mechanism of action of GV-971, and identify incidence of known adverse reactions in long-term use and observe new adverse reactions, providing more guidance for clinical use.

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