研究单位:[1]Beijing InnoCare Pharma Tech Co., Ltd.[2]The First Affiliated Hospital of Bengbu Medical College,Bengbu,Anhui,China,233000[3]Beijing Friendship Hospital, Capital Medical University,Beijing,Beijing,China,100000[4]China-Japan Friendship Hospital,Beijing,Beijing,China,100000[5]Peking University Third Hospital,Beijing,Beijing,China,100000[6]The First Affiliated Hospital of Chongqing Medical University,Chongqing,Chongqing,China,400000[7]The First Affiliated Hospital of Fujian Medical University,Fuzhou,Fujian,China,350000[8]Dermatology Hospital of Southern Medical University,Guangzhou,Guangdong,China,510000[9]Affiliated Hospital of Guizhou Medical University,Guiyang,Guizhou,China,550081[10]The Affiliated Hospital of Chengde Medical College,Chengde,Hebei,China,067032[11]The First Affiliated Hospital of Hebei Medical University,Shijia Zhuang,Hebei,China,050000[12]The Second Affiliated Hospital of Hebei Medical University,Shijiazhuang,Hebei,China,050000[13]Nanyang city first People's Hospital,Nanyang,Henan,China,473000[14]Henan Provincial People's Hospital,Zhengzhou,Henan,China,450000[15]Shiyan City People's Hospital,Shiyan,Hubei,China,442000[16]Wuhan University People's Hospital,Wuhan,Hubei,China,430000[17]Inner Mongolia Baotou Steel Hospital,Baotou,Inner Mongolia Autonomous Region,China,014000[18]Affiliated Hospital of Inner Mongolia Medical University,Hohhot,Inner Mongolia Autonomous Region,China,010000[19]Changzhou First People's Hospital,Changzhou,Jiangsu,China,213000[20]Lianyungang First People's Hospital,Lianyungang,Jiangsu,China,222000[21]Hospital of Dermatology, Chinese Academy of Medical Sciences,Nanjing,Jiangsu,China,210000[22]First Hospital of Jilin University,Changchun,Jilin,China,130000[23]Shandong Dermatology Hospital,Jinan,Shandong,China,250000[24]Huashan Hospital Affiliated to Fudan University,Shanghai,Shanghai,China,200000[25]Shanghai Dermatology Hospital,Shanghai,Shanghai,China,200000[26]Chengdu Second People's Hospital,Chengdu,Sichuan,China,610000[27]Tianjin Academy of Traditional Chinese Medicine affiliated Hospital,Tianjin,Tianjin,China,300000[28]The First Affiliated Hospital of Kunming Medical University,Kunming,Yunnan,China,650000[29]Hangzhou First People's Hospital,Hangzhou,Zhejiang,China,310000[30]Zhejiang Provincial People's Hospital,Hangzhou,Zhejiang,China,310000[31]Jiaxing second Hospital,Jiaxing,Zhejiang,China,314000[32]The First Hospital of Jiaxing,Jiaxing,Zhejiang,China,314000[33]The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,Zhejiang,China,325000
研究目的:
This is a multicenter, randomized, double-blind, placebo-controlled Phase II clinical study to evaluate ICP-488.Efficacy, safety, PK, and PD characteristics in Chinese adults with moderate to severe plaque psoriasis.