A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin
研究单位:[1]Eli Lilly and Company[2]Alliance Research Institute - Canoga Park,Canoga Park,California,United States,91304[3]Ark Clinical Research,Long Beach,California,United States,90815[4]Collaborative Neuroscience Research, LLC,Los Alamitos,California,United States,90720[5]Wolverine Clinical Trials,Santa Ana,California,United States,92705[6]CMR of Greater New Haven,Hamden,Connecticut,United States,06517[7]Institute of Endocrinology Diabetes, Health & Hormone,Stockbridge,Georgia,United States,30281[8]Elite Clinical Trials,Rexburg,Idaho,United States,83440[9]Accellacare - DuPage,Lombard,Illinois,United States,60148[10]Tandem Clinical Research,Marrero,Louisiana,United States,70072[11]St. Vincent Healthcare,Billings,Montana,United States,59101[12]Albuquerque Clinical Trials, Inc.,Albuquerque,New Mexico,United States,87102[13]Accellacare - Winston-Salem,Winston-Salem,North Carolina,United States,27103[14]Alliance for Multispecialty Research, LLC,Norman,Oklahoma,United States,73069[15]Essential Medical Research,Tulsa,Oklahoma,United States,74137[16]Accellacare - Mt Pleasant,Mount Pleasant,South Carolina,United States,29464[17]Accellacare, US Inc., d/b/a Accellacare of Knoxville,Jefferson City,Tennessee,United States,37760[18]Dallas Diabetes Research Center,Dallas,Texas,United States,75230[19]Juno Research,Houston,Texas,United States,77040[20]Consano Clinical Research, LLC,Shavano Park,Texas,United States,78231[21]The Second People''s Hospital of Hefei,Hefei,Anhui,China,230011[22]The Fourth Hospital of Harbin Medical University,Harbin,Heilongjiang,China,150001[23]The First Affiliated Hospital of Nanyang Medical College,Nanyang,Henan,China,473007[24]The Second Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan,China,450014[25]Nanjing First Hospital,Nanjing,Jiangsu,China,210006[26]The Second Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu,China,210011[27]The First Affiliated Hospital of Soochow University,Suzhou,Jiangsu,China,215006[28]Affiliated Hospital of Jiangsu University,Zhenjiang,Jiangsu,China,212000[29]Jinan Central Hospital,Jinan,Shandong,China,250013[30]Shanghai Sixth People''s Hospital,Shanghai,Shanghai,China[31]First Affiliated Hospital of Kunming Medical University,Kunming,Yunnan,China,650032[32]The First Affiliated Hospital of Wenzhou Medical University,Wenzhou,Zhejiang,China,325000[33]CRS Clinical Research Services Mannheim,Mannheim,Baden-Württemberg,Germany,68167[34]Diabetologische Schwerpunktpraxis Dr. Staudenmeyer & Dr. Schiwietz,Lingen,Niedersachsen,Germany,49808[35]Diabetes- und Stoffwechselpraxis Bochum,Bochum,Nordrhein-Westfalen,Germany,44869[36]InnoDiab Forschung Gmbh,Essen,Nordrhein-Westfalen,Germany,45136[37]Medizentrum Essen Borbeck,Essen,Nordrhein-Westfalen,Germany,45355[38]Zentrum fur klinische Forschung - Köln,Köln,Nordrhein-Westfalen,Germany,51069[39]Institut für Diabetesforschung GmbH Münster,Münster,Nordrhein-Westfalen,Germany,48145[40]Diabetologikum Ludwigshafen/Die Praxis am Ludwigsplatz,Ludwigshafen am Rhein,Rheinland-Pfalz,Germany,67059[41]Diabetologische Schwerpunktpraxis und Praxis für Allgemeinmedizin Dr. Veronika Wenzl-Bauer null Josef Wenzl,Rehlingen,Saarland,Germany,66780[42]Zentrum für klinische Studien,St.Ingbert,Saarland,Germany,66386[43]RED-Institut GmbH,Oldenburg,Schleswig-Holstein,Germany,23758[44]Diabetes Zentrum Wilhelmsburg,Hamburg,Germany,21109[45]Cryptex Investigación Clínica S.A. de C.V.,Cuauhtémoc,Distrito Federal,Mexico,06100[46]ProcliniQ Investigación Clínica SA de CV,Mexico City,Distrito Federal,Mexico,14050[47]Grupo Ollin Care,Pachuca,Hidalgo,Mexico,42000[48]Instituto Jalisciense de Investigacion en Diabetes y Obesidad,Guadalajara,Jalisco,Mexico,44600[49]Instituto de Diabetes, Obesidad y Nutricion,Cuernavaca,Morelos,Mexico,62250[50]Cardiolink Clin Trials,Monterrey,Nuevo León,Mexico,64060[51]Clínica García Flores SC,Monterrey,Nuevo León,M
研究目的:
The main purpose of this study is to assess the safety and efficacy of orforglipron compared with dapagliflozin in improving blood sugar control in participants with type 2 diabetes (T2D) with inadequate glycemic control using metformin. The study will last approximately 46 weeks.