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To Evaluate the Phase III Clinical Trial of TQH2722 Injection in the Treatment of Moderate to Severe Atopic Dermatitis

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研究单位: [1]Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. [2]The First Affiliated Hospital of Bengbu Medical College,Bengbu,Anhui,China,233004 [3]Tongling People''s Hospital,Tongling,Anhui,China,244000 [4]The Second Affiliated Hospital of Wannan Medical College,Wuhu,Anhui,China,241000 [5]Beijing Friendship Hospital, Capital Medical University,Beijing,Beijing,China,100050 [6]The First Affiliated Hospital of Chongqing Medical University,Chongqing,Chongqing,China,400010 [7]The First Affiliated Hospital of the Chinese People''s Liberation Army Army Medical University,Chongqing,Chongqing,China,400038 [8]The Second Affiliated Hospital of Chongqing Medical University,Chongqing,Chongqing,China,400072 [9]Chongqing Three Gorges Medical College affiliated People''s Hospital,Chongqing,Chongqing,China,404100 [10]The Second Affiliated Hospital of Xiamen Medical College,Xiamen,Fujian,China,361021 [11]Dermatology Hospital of Southern Medical UniversityDermatology Hospital of Southern Medical University,Guangzhou,Guangdong,China,510000 [12]The Second Affiliated Hospital of Guangzhou Medical University,Guangzhou,Guangdong,China,510000 [13]Peking University Shenzhen Hospital,Shenzhen,Guangdong,China,518036 [14]Liuzhou People''s Hospital,Liuzhou,Guangxi,China,545006 [15]Cangzhou Central Hospital,Cangzhou,Hebei,China,061012 [16]The Affiliated Hospital of Chengde Medical College,Chengde,Hebei,China,067000 [17]Heilongjiang Provincial Hospital,Ha''erbin,Heilongjiang,China,150036 [18]The Second Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,China,151100 [19]Qiqihar Hospital of Traditional Chinese Medicine,Qiqihar,Heilongjiang,China,161005 [20]Anyang District Hospital, Puyang City,Anyang,Henan,China,455001 [21]The Second Affiliated Hospital of Henan University of Science and Technology,Luoyang,Henan,China,471000 [22]Nanyang city first People''s Hospital,Nanyang,Henan,China,473000 [23]Sanmenxia Central Hospital,Sanmenxia,Henan,China,472000 [24]Henan Provincial People''s Hospital,Zhengzhou,Henan,China,450000 [25]The First Affiliated Hospital of Henan University of Science and Technology,Zhengzhou,Henan,China,471000 [26]Jingzhou Central Hospital,Jingzhou,Hubei,China,434000 [27]Wuhan University People''s Hospital,Wuhan,Hubei,China,430060 [28]Yichang Central People''s Hospital,Yichang,Hubei,China,443003 [29]The Second Xiangya Hospital, Central South University,Changsha,Hunan,China,410011 [30]Xiangya Third Hospital, Central South University,Changsha,Hunan,China,410013 [31]The First Affiliated Hospital of University of South China,Hengyang,Hunan,China,421001 [32]Hunan Medical University General Hospital,Huaihua,Hunan,China,418000 [33]The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology,Baotou,Inner Mongolia,China,14017 [34]Baotou Central Hospital,Baotou,Inner Mongolia,China,14040 [35]Affiliated Hospital of Inner Mongolia Medical University,Hohhot,Inner Mongolia,China,10000 [36]Changzhou First People''s Hospital,Changzhou,Jiangsu,China,213000 [37]The Second Affiliated Hospital of Soochow University,Suzhou,Jiangsu,China,215000 [38]Suzhou Municipal Hospital,Suzhou,Jiangsu,China,Weiling [39]Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu,China,221132 [40]Yancheng First People''s Hospital,Yancheng,Jiangsu,China,224005 [41]Affiliated Hospital of Jiangsu University,Zhenjiang,Jiangsu,China,210039 [42]The Second Affiliated Hospital of Nanchang University,Nanchang,Jiangxi,China,330006 [43]Second Hospital of Jilin University,Changchun,Jilin,China,130041 [44]Panjin Liao oil precious stone flower hospital,Panjin,Liaoning,China,124120 [45]Yinchuan First People''s Hospital,Yinchuan,Ningxia,China,750010 [46]Affiliated Hospital of Qinghai University,Xining,Qinghai,China,810000 [47]Dezhou People''s Hospital,Dezhou,Shandong,China,277102 [48]Shandong University Qilu Hospital,Jinan,Shandong,China,250012 [49]Liaocheng People''s Hospital,Liaocheng,Shandong,China,252000 [50]Yantai Yuhuangding Hospital,Yantai,Shandong,China,264000 [51]Zaozhuang Municipal Hospital,Zaozhuang,Shandong,China,277102 [52]Shanghai Dermatology Hospital,Shanghai,Shanghai,China,545006 [53]Baoji Central Hospital,Baoji,Shanxi,China,721008 [54]Shanxi Provincial People''s Hospital,Taiyuan,Shanxi,China,030000 [55]Peking University First Hospital Taiyuan Hospital,Taiyuan,Shanxi,China,030009 [56]The Second Affiliated Hospital of Xi ''an Jiaotong University,Xi''an,Shanxi,China,710004 [57]The First Affiliated Hospital of PLA Air Force Medical University,Xi''an,Shanxi,China,710032 [58]The First Affiliated Hospital of Xi ''an Medical College,Xi''an,Shanxi,China,710032 [59]The Second Affiliated Hospital of the Chinese People''s Liberation Army Air Force Medical University,Xi''an,Shanxi,China,710032 [60]Chengdu Second People''s Hospital,Chengdu,Sichuan,China,610000 [61]Sichuan Provincial People''s Hospital,Chengdu,Sichuan,China,610000 [62]Chengdu Second People''s Hospital,Chengdu,Sichuan,China,610072 [63]Affiliated Hospital of Southwest Medical University,Luzhou,Sichuan,China,646000 [64]Suining Central Hospital,Suining,Sichuan,China,629000 [65]Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital,Tianjin,Tianjin,China,300120 [66]Tianjin First Central Hospital,Tianjin,Tianjin,China,300190 [67]People''s Hospital of Xinjiang Uygur Autonomous Region,Ürümqi,Xinjiang,China,830002 [68]Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine,Ürümqi,Xinjiang,China,830002 [69]The First Affiliated Hospital of Kunming Medical University,Kunming,Yunnan,China,650032 [70]Hangzhou First People''s Hospital,Hangzhou,Zhejiang,China,310006 [71]Hangzhou Third People''s Hospital,Hangzhou,Zhejiang,China,310009 [72]Jiaxing second Hospital,Jiaxing,Zhejiang,China,545006 [73]Jinhua Central Hospital,Jinhua,Zhejiang,China,321000 [74]The First Affiliated Hospital of Ningbo University,Ningbo,Zhejiang,China,315211

研究目的:
This is a randomized, double-blind, placebo-controlled clinical trial with 500 participants. In this study, the safety evaluation used the common toxic reaction criteria of the National Cancer Institute to evaluate the adverse events of the drugs, and the effectiveness evaluation used the eczema area and severity score and the overall investigator score to confirm the efficacy.

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