研究单位：[1]Sun Yat-sen University[2]Tianjin Medical University Cancer Institute and Hospital[3]RenJi Hospital[4]Sixth Affiliated Hospital, Sun Yat-sen University[5]First Affiliated Hospital of Jinan University[6]The First Affiliated Hospital with Nanjing Medical University[7]Hebei Medical University Fourth Hospital[8]Shanghai Changzheng Hospital[9]Cancer Institute and Hospital, Chinese Academy of Medical Sciences[10]Suining Central Hospital[11]Ningbo Medical Center Lihuili Hospital[12]Shanxi Provincial Cancer Hospital[13]The Affiliated Hospital of Xuzhou Medical University[14]The General Hospital of Eastern Theater Command[15]First Affiliated Hospital, Sun Yat-Sen University[16]Guangdong Provincial People's Hospital[17]Fujian Medical University Union Hospital[18]First Affiliated Hospital of Kunming Medical University[19]Fujian Provincial Hospital[20]Tianjin Chest Hospital[21]Sichuan Cancer Hospital and Research Institute[22]Shenzhen People's Hospital[23]Tang-Du Hospital[24]Shandong Provincial Hospital[25]Gansu Provincial Hospital[26]Wuhan Union Hospital, China[27]Wuhan TongJi Hospital[28]The Affiliated Hospital of Qingdao University[29]West China Hospital[30]The First Affiliated Hospital of Nanchang University[31]Jiangsu Cancer Institute & Hospital[32]Dongguan People's Hospital[33]First People's Hospital of Foshan
During the surgery for non-small cell lung cancer (NSCLC), lymphadenectomy or lobectomy are performed first, different surgeons have different choices. Oncology textbooks require dissecting distant lymph nodes (LNs) first and then dissecting nearby LNs. According to this requirement, thoracic surgeons should first perform lymphadenectomy and then lobectomy. Unfortunately, there is no high-level evidence to prove which surgical sequence is more beneficial to the long-term survival of NSCLC patients. In this multi-center randomized controlled trial (RCT), patients with stage I-II NSCLC were enrolled as the research object to determine which surgical sequence (lymphadenectomy-first vs. lobectomy-first) is better for the short-term and long-term outcomes in NSCLC patients.
