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一项评估口服Ozanimod 治疗中度至重度活动性克罗恩病的扩展研究

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研究单位: [1]浙江大学医学院附属邵逸夫医院 [2]中国人民解放军总医院第七医学中心 [3]广州市第一人民医院 [4]华中科技大学同济医学院附属同济医院 [5]华中科技大学同济医学院附属协和医院 [6]首都医科大学附属北京友谊医院 [7]南京医科大学第一附属医院(江苏省人民医院) [8]南昌大学第一附属医院 [9]安徽省立医院 [10]上海市东方医院 [11]郑州大学第二附属医院 [12]天津医科大学总医院 [13]昆明医科大学第一附属医院 [14]东南大学附属中大医院 [15]吉林大学中日联谊医院 [16]中南大学湘雅二医院 [17]上海市第一人民医院 [18]蚌埠医学院第一附属医院 [19]复旦大学附属华山医院 [20]无锡市人民医院 [21]北京大学第三医院 [22]西南医科大学附属医院 [23]常州市第一人民医院 [24]中国人民解放军第四军医大学唐都医院 [25]上海交通大学医学院附属新华医院 [26]长海医院 [27]南京鼓楼医院 [28]四川大学华西医院 [29]西安国际医学中心 [30]中南大学湘雅医院 [31]福建医科大学附属第一医院 [32]上海交通大学医学院附属瑞金医院 [33]广东省人民医院 [34]Sanatorio 9 de Julio S.A.-CICE 9 de Julio [35]Hospital Privado Centro Médico de Cordoba [36]Hospital Provincial del Centenario [37]CER Medical Institute-Quilmes [38]Diagnostic&Therap-ic Gastro-gy [39]Alfred Hospital [40]Liverpool Hospital [41]Concord Repatriation General Hosptial [42]John Hunter Hospital [43]Nepean Hospital [44]Wollongong Hospital [45]Princesss Alexandra Hospital [46]Mater Hospital Brisbane [47]Coastal Digestive Health Pty L [48]Zuellig Pharma SSG Australia [49]Royal Adelaide Hospital [50]Queen Elizabeth Hospital [51]St Vincent's Hospital Melbourne [52]Monash Health [53]Medical University Vienna [54]University Hospital Innsbruck [55]University Hospital St.Poelten [56]Vitebsk Regional Center [57]Grodno City Hospital #4 [58]Clinique du Montlégia [59]Sart Tilman Hospital,Department of Gastroenterology and Hepatology [60]University Hospital Antwerp (UZA) [61]University Hospital Brussels [62]University Hospitals Leuven [63]University Clinical Centre of [64]Medical Center Synexus Sofia [65]Medical Center Synexus Sofia [66]Medline Multiprofile Hospital [67]ACIBADEM City Clinic [68]Sveti Ivan Rilski Hospital [69]ACIBADEM City Clinic Tokuda Ho [70]Tsaritsa Yoanna ISUL Hospital [71]Kanev University Hospital [72]LHSC - Victoria Hospital [73]London Health Sciences Centre - University Hospital [74]Brandon Medical Arts Clinic [75]Kensington Screening Clinic [76]Fraser Clinical Trials,Inc [77]Mount Sinai Hospital [78]G.I. Research Institute (G.I.R.I.) [79]Allen Lim Professional Corp [80]The Ottawa Hospital - General Campus [81]Toronto Digestive Disease Associates Inc [82]University of Calgary [83]CECIM [84]De La Costa Clinic Ltd. [85]University Hospital Zagreb [86]Military Hospital Brno [87]Hepato-Gastroenterology HK s.r [88]St. Anne's University Hospital [89]Gastroenterology and Endoscopy [90]Synexus Czech s.r.o. [91]PreventaMed s.r.o. [92]Regional Hospital Pardubice [93]Institute of Clinical and Experimental Medicine (IKEM) [94]ISCARE a.s. [95]Creteil Intercommunal Hospital [96]Amiens Picardie Hospital [97]North Hospital [98]Hopital Claude Huriez [99]South Lyon Hospital Center [100]Nantes University Hospital [101]Blois Hospital [102]North Hospital [103]Hopital Albert Michallon [104]Hospital Pontchaillou [105]Beaujon Hospital [106]Louis Mourier Hospital [107]University Hospital of Rouen [108]Hospital de Rangueil [109]Dijon University Hospital [110]University Hosp. Center Caen [111]Medical Center [112]Israeli-Georgian MRC Helsicore [113]JSC Evex Medical Corporation [114]David Tatishvili Medical Cente [115]LLC 'Vivamedi' [116]LTD Central University Clinic [117]JSC Infectious Disease [118]LTD Aversi Clinic [119]JSC Evex Medical Corporation [120]Clinical Cardiology Institute [121]Medius Clinic Nuertingen [122]University Hospital Ulm [123]University Hospital Tuebingen [124]Medical Care Unit Dachau [125]Charite University Hospital [126]Hospital Waldfriede e.V. [127]Charite University Hospital [128]DRK Clinics Berlin [129]Charite Hospital Berlin [130]Ruppinen Hospital Ltd. [131]Brandenburg City Hospital [132]Univ. Hosp. Hamburg-Eppendorf [133]Crohn Colitis Cent. Rhein Main [134]J W Goethe University Hospital [135]Synexus Clinical Research GmbH [136]Synexus Leipzig Research Centr [137]University Hospital Muenster [138]Agaplesion Markus Hospital [139]Practice for Gastroenterology [140]St.Marien-u. St.Annastifts-KH [141]University Hospital Leipzig [142]University Hospital Halle (Saale) [143]Studiengesellschaft BSF [144]Univ. Hosp. Schleswig-Holstein [145]Alexandra General Hospital [146]Metropolitan General [147]Thessaloniki General Hospital [148]Queen Mary Hospital [149]SYNEXUS Hungary [150]Synexus Hungary Ltd. [151]Bekescsaba Rethy Pal Hospital [152]Fejer County St. Gyorgy Unive [153]Kanizsai Dorottya Hospital [154]Petz Aladar County Hospital [155]Medical Centre,Defence Forces [156]Semmelweis University [157]Csongrad County Hospital [158]Clinfan Ltd [159]Beaumont Hospital [160]St Vincent's University Hospital [161]Kaplan Medical Center,GI and Liver Disease Institute [162]Shaare Zedek Medical Center [163]Gastroenterology Division,Rabin Medical Center,Beilinson Campus [164]Gastroenterology Department,Outpatient Clinics,unit 9Sheba Medical Center [165]IBD unit,Institute of Gastroenterology and Liver Diseases,Emek Medical Center [166]Meir Medical Center,Gastroenerology &HepatologyStulberg Building [167]Rambam Health Care Campus [168]Hospital S. Camillo Forlanini [169]Humanitas Research Hospital [170]Polyclinic San Matteo,IRCCS [171]Mater Domini [172]Agostino Gemelli [173]Sacred Heart Don Calabria [174]Polyclinic S. Orsola-Malpighi [175]ASST Monza [176]Mater Domini [177]Integrated University Hospital [178]Hospitals Villa Sofia Cervello [179]Civil Hospital of Brescia [180]Hospital of Padova [181]Ss. Annunziata [182]Poliambulanza Hospital [183]IRCCS [184]Kangbuk Samsung Hospital [185]The Catholic University of Korea St.Vincents Hospital [186]Severance Hospital,Yonsei University Health System [187]InJe University Haeundae Paik Hospital [188]Yeungnam University Hospital [189]Samsung Medical Center [190]Hanyang University Guri Hospital [191]Seoul National University Bundang Hospital [192]Seoul National University Hospital [193]Clinical Trial Center [194]Dong-A Medical Center [195]LLC Digestive Diseases Centre [196]P Stradins Clinical University [197]Investigacion Biomedica para el desarrollo de Farmacos,S.A. de C.V. [198]Centro de Investigacion Clinica Acelerada (CICA) S.C. [199]ICARO Investigaciones en Medicina S.A. de C.V. [200]SMIQ [201]Instituto Nacional de Ciencias Médicas y Nutricion Salvador Zubiran ( INCMNSZ) [202]Centro Regiomontano de Estudios Clinicos Roma [203]PMSI [204]Sfanta Treime [205]Sf. Arhanghel Mihail Hospital [206]PMSI [207]Radboud Univ Medical Center [208]Zuyderland Medical Center [209]St. Elisabeth Hospital [210]Academic Medical Center [211]University Medical Center Groningen (UMCG) [212]MDM Healthcare Centre [213]Synexus Polska Sp. z o.o. [214]Synexus Polska Sp. z o.o. [215]Synexus Polska Sp. z o.o. [216]Synexus Polska Sp. z o.o. [217]Synexus Polska Sp. z o.o. [218]Synexus Polska Sp. z o.o. [219]Synexus Polska Sp. z o.o. [220]Synexus Polska Sp. z o.o. [221]WIP Warsaw IBD Point [222]BioVirtus Medical Centre [223]SOLUMED Medical Center [224]1st Military Teaching Hospital [225]GLOBE Clinical Research [226]MaxMed Medical Services Centre [227]Kornel Gibinski Hospital [228]Jedrzej Sniadecki Hospitals [229]Landa Specialist Doctor's Of [230]H-T Medical Center Endotherapy [231]Krakow Medical Center,LLC [232]ETG Kielce Zagorska [233]SANTA FAMILIA Research [234]Provincial Specialist Hospital [235]LEXMEDICA [236]EuroMediCare [237]Orkan-Med Healthcare Centre [238]TWOJA PRZYCHODNIA Medical Centre of Szczecin [239]Salve Limited Company [240]Metabolic Diseases Clinic [241]Private Medical Practice M.Fic [242]Office of Korczowski Bartosz [243]Allmedica Clinical Trials [244]D.Kleczkowski Medical Practice [245]Clinical Research Center [246]LUX MED Sp. z o.o. (LLC) [247]Jan Mikulicz Radecki University Hospital in Wroclaw [248]PlanetMed Gastroenterology [249]Barbara Wozniak-Stolarska [250]Local Unit of Health Alto Minh [251]Targu Mures County Hospital [252]Hospital Beatriz Angelo [253]Univ Hospital Center Coimbra [254]Provita Center of Diagnosis [255]Hyperclinic MedLife Grivita [256]Hyperclinic MedLife Grivita [257]Fundeni Clinical Institute [258]Colentina Clinical Hospital [259]University Emergency Hospital [260]Carol Davila Military Hospital [261]Territorial Clinical Hospital [262]Diagnostic Center Bioterm Ltd. [263]Chelyabinsk Regional Hospital [264]Irkutsk State Medical Academy [265]Immanuel Kant Baltic Federal University [266]S.V. Beliaev Regional Hospital [267]Siberian Research Clin. Center [268]Clinical and Diagnostic Center [269]St. Elizabeth Hospital [270]Kirov Military Medical Academy [271]City Clinical Hospital #31 [272]City Outpatient Care Unit #38 [273]OLLA MED,LLC [274]V.M. Buyanov City Hospital [275]Regional Clinical Hospital [276]Novgorod Regional Clinical Hos [277]Railway Station Hospital [278]Novosibirskiy Gastrocentr [279]Medical Center Sibnovomed,LLC [280]Medical Diagnostic Center,LLC [281]N.N. Burdenko Penza Hospital [282]Primorsky Reg. Hospital No 1 [283]Myod Ltd. [284]Rostov State Medical Univ. [285]Samara Station Railway Hospita [286]Medical University [287]EVROMEDSERVIS Private Medical [288]I.I. Mechnikov State Univ. [289]S.M. Kirov Military Medical Ac [290]Regional Clinical Hospital [291]Clinic UZI 4D,LLC [292]Pyatigorsk City Clinical Hospi [293]Medical Technologies [294]MA [295]Kazan City Clinical Hospital 7 [296]Tomsk Regional Clinical Hospit [297]Tula Clinical Hospital [298]Regional Clinical Hospital [299]Chita State Medical Academy [300]King Abdulaziz Medical city,National guard hospital,Riyadh [301]King Khalid University Hospital [302]King AbdulAziz University Hospital Jeddah [303]General Hospital Vrsac [304]Dr. Dragisa Misovic-Dedinje [305]General Hospital Pancevo [306]Military Medical Academy [307]Bezanijska Kosa Hospital Cente [308]General Hospital [309]Zvezdara UMC [310]Clinical Center Kragujevac [311]World of the Health Inc. [312]Gastromedic,s.r.o. [313]GASTRO I,s.r.o. [314]Cliniq,s.r.o. [315]General Hospital Celje [316]Emmed Research [317]Lenasia Clinical Trial Centre [318]Clinresco Centres [319]University Hospital Alicante [320]Univ. Hospital de La Princesa [321]Puerta de Hierro Majadajonda [322]University Hospital La Paz [323]Dr Negrin University Hospital [324]Hospital of Girona Dr.J.Trueta [325]Teknon Medical Center [326]University Hospital Marques de Valdecilla (HUMV),Department of Gastroenterology [327]HUC La Laguna [328]Germans Trias i Pujol Hospital [329]Viladecans Hospital [330]Hospital Reina Sofia [331]Lindenhofspital [332]Cantonal Hospital Saint Gallen [333]China Medical University Hospital [334]National Cheng Kung University Hospital [335]Chang Gung Medical Hospital - LINKOU [336]National Taiwan University Hospital [337]Goztepe Prof. Suleyman Yalcin [338]Kocaeli University Medical Fac [339]Hacettepe Universitesi Hastanesi [340]Karadeniz Teknik Universitesi Farabi Hastanesi [341]Istanbul Sultanabdülhamit Han Egitim Arastirma Hastanesi [342]Bezmialem Vakif Universitesi Hastanesi [343]Bulent Ecevit Universitesi Uygulama ve Arastirma Hastanesi [344]Synexus Midlands Clin Centre [345]Southampton General Hospital [346]Blackpool Victoria Hospital [347]Guy's Hospital [348]Royal London Hospital [349]Synexus Hexham Research Centre [350]Synexus Wales CRC [351]Royal Shrewsbury Hospital [352]University College Hospital [353]Chernivtsi Regional Hospital [354]Institute of Gastroenterology [355]Ivano-Frankivsk Central Hospit [356]Ivano-Frankivsk Reg. Hospital [357]O.O. Shalimov City Hospital #2 [358]Khmelnytskyi Regional Hospital [359]Medical Center [360]Kyiv City Clinical Hospital 18 [361]Kyiv Regional Clinical Hospita [362]Ok! Clinic [363]Consylium Medical Center [364]Kyiv Regional Hospital #2 [365]Kyiv Regional Clinical Hospita [366]Lviv Regional Clinical Hospita [367]CENTER OF FAMILY MEDICINE PLUS [368]EDELWEISS MEDICS [369]Medical Center within 'Medbud' [370]Odesa Regional Clin. Hospital [371]Poltava Sklifosovskyi Hospital [372]Vinnytsia City Clinical Hosp 1 [373]Vinnytsia M.I.Pyrohov Hospital [374]Health Clinic,LLC [375]M.I. Pyrohov Regional Hospital [376]Clinic of the St. Nicholas [377]Zaporizhia Regional Hospital [378]Volyn Regional Clin.Hospital [379]HonorHealth Research Institute [380]Arkansas Gastroenterology,P.A. [381]Medical Associates Research Group [382]Inland Empire Liver Foundation [383]OM Research LLC [384]VVCRD Clinical Research [385]University of Southern California [386]Gastrointestinal Biosciences [387]Sharp Chula Vista Medical Center [388]University of California,Davis [389]University of California San Francisco [390]Peak Gastroenterology Associates [391]Yale University - Digestive Disease [392]Connecticut Clinical Research Institute [393]IMIC,Inc. [394]Florida Center for Gastroenterology [395]Galiz Research [396]Gastroenterology Consultants of Clearwater [397]Alliance Medical Research LLC [398]HMD Research LLC [399]Advanced Medical Research Center [400]Guardian Angel Research [401]Universal Axon Clinical Research [402]Research Associates of South Florida [403]Life Medical Center & Research,Inc [404]The Center for Gastrointestinal Disorders [405]University of South Florida [406]Bayside Clinical Research [407]Nova Clinical Research Center Inc [408]Omega Research Maitland [409]Qway Research LLC [410]NSB Research [411]University of Florida Health (UF) [412]Atlanta Gastroenterology Associates [413]Gastroenterology Associates of Central Georgia [414]Emory University [415]Children's Center for Digestive Health Care [416]Gastrointestinal Disease Research [417]Atlanta Center for Gastroenterology,P.C. [418]Consultative Gastroenterology [419]Grand Teton Research Group,PLLC [420]University of Chicago Medicine [421]Northwestern Feinberg School of Medicine [422]Rush University Medical Center - University Cardiovascular Surgeons [423]Southwest Gastroenterology [424]Indiana University Hospital [425]Medisphere Medical Research Center,LLC [426]Cotton-O'Neil Clinical Research Center,Digestive Health [427]University of Kentucky Chandler Medical Center [428]Gastroenterology Associates,LLC [429]Digestive Disease Associates,PA [430]Woodholme Gastroenterology Associates [431]University of Massachusetts Memorial Medical Center [432]Brigham and Women's Hospital [433]Henry Ford Health System [434]Revival Research Institute LLC [435]Western Michigan University Homer Stryker M.D. School fo Medicine [436]Caro Health Plaza [437]Mayo Clinic [438]University of Minnesota [439]Southern Therapy and Advanced Research [440]Washington University School of Medicine [441]Mid America Gastrointestinal Consultants [442]Dartmouth-Hitchcock Medical Center [443]Northwell Health [444]Lenox Hill Hospital - Northwell Health [445]Drug Trials America [446]DiGiovanna Institute for Medical Education and Research [447]Weill Cornell Medicine [448]NY Scientific/Igor Grosman [449]PMG Research of Winston-Salem,LLC [450]Carolina Research/Carolina Digestive Diseases [451]CHS - Center for Digestive Health [452]PMG Research of Charlotte,LLC [453]Cleveland Clinic [454]The Ohio State University Wexner Medical Center [455]Advance Clinical Research [456]Ohio GI and Liver Institute [457]Central Sooner Research [458]Digestive Disease Specialists Inc [459]Vital Prospects Clinical Research Institute,PC [460]University of Oklahoma Health Sciences Center [461]Essential Medical Research,LL [462]Oregon Health and Science University [463]Penn State Milton S Hershey Medical Center [464]Gastroenterology Associates of Orangeburg [465]Medical Univ of S Carolina [466]Texas Digestive Disease Consultants [467]Brooke Army Medical Center [468]Houston Methodist [469]DHAT Research Institute [470]Tyler Research Institute [471]Sun Research Institute [472]Baylor College of Medicine [473]Avant Research Associates,LLC [474]San Antonio Gastroenterology Associates Clinical Trials (SAGACT) [475]Baylor Scott & White [476]The Coastal Medical Group [477]The University of Utah Health Sciences Center [478]Blue Ridge Medical Research [479]McGuire DVAMC [480]Carilion Clinic [481]Gleason Research,LLC [482]Mayo Clinic Health System - Franciscan Healthcare

研究目的:
这是一项评估口服OZANIMOD 作为中度至重度活动性克罗恩病的维持治疗的III 期、多中心、随机、双盲、安慰剂对照研究

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