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Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular Coagulation

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研究单位: [1]China Medical University,China [2]the Second Affiliated Hospital of Kunming University Kunming,Yunnan,China [3]Beijing Friendship Hospital,Capital Medical University Beijing,China [4]Changgeng Hospital of Tsinghua University Beijing,China [5]People's Hospital of Peking University Beijing,China [6]First Affiliated Hospital of Jilin Medical University Jilin,China [7]Qinhuangdao First Hospital Qinhuangdao,China [8]Liaoning Provincial People's Hospital Shenyang,China [9]The fist Affiliated Hospital Harbin Medical University Haerbin,Heilongjiang,China [10]First Affiliated Hospital of Kunming Medical University Kunming,Yunnan,China

研究目的:
The primary objective of this study is to estimate the efficacy of unfractionated heparin(UFH) on ICU mortality in severe sepsis with suspected DIC.The Second objective is to estimate the effect of UFH on 28-day mortality,and the change of the Japanese Association for Acute Medicine(JAAM) score and SOFA score. The third one is to evaluate the safety of UFH in severe sepsis patients with suspected DIC.

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