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Roux-en-Y vs. Roux-en-Y+ Pouch for D2 Total Gastrectomy (WCGCC-1202)

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研究单位: [1]West China Hospital [2]Xinqiao Hospital,Third Military Medical University Chongqing,Chongqing,China,404100 [3]First Affiliated Hospital of Lanzhou University Lanzhou,Gansu,China,730000 [4]Union Hospital,Tongji Medical College Wuhan,Hubei,China,430000 [5]First Affiliated Hospital of Xi'an Jiaotong University School of Medicine Xian,Shanxi,China,710000 [6]Tangdu Hospital,Fourth Military Medical University Xian,Shanxi,China,710000 [7]Xijing hospital,Fourth Military Medical University Xian,Shanxi,China,710000 [8]West China Hospital,Sichuan University Chengdu,Sichuan,China,610041 [9]First Affiliated Hospital of Kunming medical University Kunming,Yunnan,China,650000

研究目的:
Gastric is one of the most prevalence digestive malignance tumors in China. Radical resection of primary tumors and combine with dissection of regional lymph-nodes is acknowledged by surgeons all over the world. Nowadays, in order to improve the quality of life, controversies still exist to the reconstruction methods of total gastrectomy. Although roux-en-y anastomosis is the most common method adopted after total gastrectomy for it is an easily and safety method reconstruction method, but some problems still need us to solve, such as little food reserves, less food intake per meal and fast gastric emptying. These problems significantly affect the patients' quality of life after surgery. Roux-en-Y+Jejunal pouch anastomosis is newly born method can significant increase the volume to improve postoperative quality of life have been proven by some little sample size randomized control trail With the improvement of the gastric cancer surgery, this study proposed by prospective randomized controlled clinical trials aimed to comparing quality of life after traditional Roux-en-Y type and Roux-en-Y+ Jejunal pouch type anastomosis for radical total gastrectomy. Quality of life was evaluated according to the European Organization for Research and Treatment of Cancer (EORTC) Quality Of Life Questionnaire (QLQ)-C30 and QLQ-STO22. Quality of life will conducted in the 3 months, 6 months, 9 months, 12 months, 24 months, 36 months after gastrectomy.

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