研究单位：[1]Sun Yat-sen University[2]Shantou Central Hospital[3]Liaoning Tumor Hospital & Institute[4]The First Affiliated Hospital with Nanjing Medical University[5]Fujian Cancer Hospital[6]Guangdong Provincial Hospital of Traditional Chinese Medicine[7]First Affiliated Hospital of Chongqing Medical University[8]The First Affiliated Hospital of Guangzhou Medical University[9]Guangdong Provincial People's Hospital[10]Cancer Hospital of Guangxi Medical University[11]Meizhou People's Hospital[12]Henan Cancer Hospital[13]Affiliated Cancer Hospital of Shantou University Medical College[14]Hubei Cancer Hospital[15]The First Affiliated Hospital of Kunming Medical College[16]Longyan City First Hospital[17]Shengjing Hospital[18]Zhejiang Cancer Hospital[19]Jiangmen Central Hospital[20]West China Hospital[21]The Third Affiliated Hospital of Kunming Medical College
研究目的：
Although neoadjuvant radiotherapy greatly decreases local recurrence in locally advanced rectal cancer patients undergoing surgery, it inevitably results in short-term and long-term toxicities. More importantly, it has not been confirmed that neoadjuvant radiotherapy could improve overall survival. The purpose of this study is to compare the effects of chemotherapy alone using a combination regimen known as XELOX (capecitabine and oxaliplatin ) and selective use of the standard treatment to the standard treatment of chemotherapy and radiation.
