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Management of regional citrate anticoagulation for continuous renal replacement therapy: guideline recommendations from Chinese emergency medical doctor consensus

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执笔作者机构: [1]Emergency Department, The Sixth Medical Center, Chinese PLA General Hospital, Beijing 100048, China. [2]State Key Laboratory of Complex Severe and Rare Diseases, Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China. [3]Emergency Department, Peking University Shenzhen Hospital, Shenzhen 518000, China.
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关键词: Continuous renal replacement therapy Emergency Anticoagulation Citrate Guideline Expert consensus

摘要:
Continuous renal replacement therapy (CRRT) is widely used for treating critically‐ill patients in the emergency department in China. Anticoagulant therapy is needed to prevent clotting in the extracorporeal circulation during CRRT. Regional citrate anticoagulation (RCA) has been shown to potentially be safer and more effective and is now recommended as the preferred anticoagulant method for CRRT. However, there is still a lack of unified standards for RCA management in the world, and there are many problems in using this method in clinical practice. The Emergency Medical Doctor Branch of the Chinese Medical Doctor Association (CMDA) organized a panel of domestic emergency medicine experts and international experts of CRRT to discuss RCA‐related issues, including the advantages and disadvantages of RCA in CRRT anticoagulation, the principle of RCA, parameter settings for RCA, monitoring of RCA (mainly metabolic acid–base disorders), and special issues during RCA. Based on the latest available research evidence as well as the paneled experts’ clinical experience, considering the generalizability, suitability, and potential resource utilization, while also balancing clinical advantages and disadvantages, a total of 16 guideline recommendations were formed from the experts’ consensus.

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收录情况: ◇统计源期刊 ◇CSCD-C ◇卓越:梯队期刊

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大类 | 2 区 医学
小类 | 2 区 医学:内科
专家组成员:
Ting Yang (Emergency Department, The First Affiliated Hospital of Kunming Medical University, Kunming 650000, China.) Kui Jin (Emergency Department, The First Affiliated Hospital of University of Science and Technology of China, Hefei 230001, China.) Qiu‑Bin Zhang (Emergency Department, The Second Affiliated Hospital of Hainan Medical College, Haikou 570100, China.) Feng Sun (Emergency Department, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.) Ding‑Yu Tan (Emergency Department, Northern Jiangsu People’s Hospital, Clinical Medical College of Yangzhou University, Yangzhou 225001, China.) Tian‑Yu Xin (Emergency Department, The Sixth Medical Center, Chinese PLA General Hospital, Beijing 100048, China.) Yu‑Guo Chen (Emergency Department and Chest Pain Center, Qilu Hospital of Shandong University, Jinan 100005, China.;Shandong Provincial Clinical Research Center for Emergency and Critical Care Medicine, Jinan 100005, China.;Key Laboratory of Emergency and Critical Care Medicine of Shandong Province, Qilu Hospital of Shandong University, Jinan 100005, China.) Xiao‑Dong Zhao (Emergency Department, The Fourth Medical Center, Chinese PLA General Hospital, Beijing 100048, China.) Xue‑Zhong Yu (State Key Laboratory of Complex Severe and Rare Diseases, Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.) Jun Xu (State Key Laboratory of Complex Severe and Rare Diseases, Emergency Department, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China.)
本院专家组成员:
Ting Yang[4] (Emergency Department, The First Affiliated Hospital of Kunming Medical University, Kunming 650000, China.)
通讯作者:
Yu‑Guo Chen (chen919085@sdu.edu.cn) Xiao‑Dong Zhao (zxd63715@126.com) Xue‑Zhong Yu (yxz@pumch.cn) Jun Xu (xujunfree@126.com)
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