机构:[1]Department of Imaging, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China.医技科室医学影像中心昆明医科大学附属第一医院[2]Department of Pathology, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China医技科室病理科昆明医科大学附属第一医院
Pulmonary alveolar proteinosis (PAP) is a rare respiratory system disorder. Patients with PAP are at risk for a wide variety of secondary infections. This current case report describes a patient with PAP complicated by tuberculosis. A 48-year-old male patient with multiple follow-up chest computed tomography scans that showed predominant diffuse ground glass opacity in both lung fields, presented a few years later with new calcified lesions and pleural effusion. At this point, the associated auxiliary examination indicated the possibility of PAP combined with tuberculosis infection. The patient achieved complete remission after anti-tuberculosis treatment. PAP is an easily overlooked clinical syndrome due to its low prevalence and lack of specific clinical manifestations, especially when combined with other pulmonary lesions. Therefore, clinicians should consider this rare disease in patients presenting with pulmonary disease and plan for its co-morbidity with other secondary outcomes, such as opportunistic infections, which are a common and life-threatening complication in patients with PAP. This case indicates the possibility that anti-tuberculosis therapy can improve alveolar proteinosis in patients with PAP and secondary Mycobacterium tuberculosis infection.
基金:
Yunnan Provincial
Clinical Medical Research Center Subproject
(202102AA100067), the Doctoral Foundation
of the First Affiliated Hospital of Kunming
Medical University (2021BS012), the Graduate
Innovation Fund Project of Kunming Medical
University (2022S058), and the Applied Basic
Research Project of Yunnan ProvinceKunming Medical University Joint Fund
(202001AY070001-200).
语种:
外文
WOS:
PubmedID:
中科院(CAS)分区:
出版当年[2023]版:
大类|4 区医学
小类|4 区医学:研究与实验4 区药学
最新[2023]版:
大类|4 区医学
小类|4 区医学:研究与实验4 区药学
JCR分区:
出版当年[2022]版:
Q4MEDICINE, RESEARCH & EXPERIMENTALQ4PHARMACOLOGY & PHARMACY
最新[2023]版:
Q4MEDICINE, RESEARCH & EXPERIMENTALQ4PHARMACOLOGY & PHARMACY
第一作者机构:[1]Department of Imaging, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China.
共同第一作者:
通讯作者:
通讯机构:[1]Department of Imaging, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China.[*1]Department of Imaging, First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Daguan Street, Wuhua District, Kunming, Yunnan 650032, China
推荐引用方式(GB/T 7714):
Fan Guangtao,Huang Yilong,Xue Fenglin,et al.Complete remission of pulmonary alveolar proteinosis after anti-tuberculous chemotherapy: a case report[J].JOURNAL OF INTERNATIONAL MEDICAL RESEARCH.2022,50(7):3000605221113785.doi:10.1177/03000605221113785.
APA:
Fan Guangtao,Huang Yilong,Xue Fenglin&He Bo.(2022).Complete remission of pulmonary alveolar proteinosis after anti-tuberculous chemotherapy: a case report.JOURNAL OF INTERNATIONAL MEDICAL RESEARCH,50,(7)
MLA:
Fan Guangtao,et al."Complete remission of pulmonary alveolar proteinosis after anti-tuberculous chemotherapy: a case report".JOURNAL OF INTERNATIONAL MEDICAL RESEARCH 50..7(2022):3000605221113785