Coronary artery disease (CAD), caused by coronary artery occlusion, is a common cardiovascular disease worldwide. Long non-coding RNAs (lncRNAs) are implicated in the regulation of endothelial cell injury, angiogenesis, plaque formation, and other pathological mechanisms in CAD by acting on different cell types. Some lncRNAs are significantly upregulated in CAD patients; however, other lncRNAs are significantly downregulated. Differential expression of lncRNAs in CAD patients enables them to be exploited as potential biomarkers to evaluate disease progression and diagnosis/prognosis in CAD patients. In this study, we reviewed the role of lncRNAs in the development of different clinical subtypes of CAD.
基金：
National Natural Science Foundation of China [81860073, 82160439]; Special Foundation Projects of Joint Applied Basic Research of Yunnan Provincial Department of Science and Technology with Kunming Medical University; Yunnan Provincial Department of Science and Technology [H-2018032]; Yunnan Health Training Project of High Level Talents [60118260106]; 100 Young and Middle-aged Academic and Technical Backbones of Kunming Medical University [YNQR-QNRC-2019-006]; Young Talents of Yunnan Thousand Talents Plan [RLQN20200002, ZX2019-03-01]; Clinical Medical Center for Cardiovascular and Cerebrovascular Disease of Yunnan Province [2019FE001(-138)]; [202001AT070039]
第一作者机构：[1]Kunming Med Univ, Dept Cardiol, Affiliated Hosp 1, Kunming 650032, Yunnan, Peoples R China
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推荐引用方式(GB/T 7714)：
Wu Xinyu,Li Jingru,Sun Guihu,et al.Role of LncRNAs in the Pathogenesis of Coronary Artery Disease[J].REVIEWS IN CARDIOVASCULAR MEDICINE.2023,24(4):doi:10.31083/j.rcm2404096.
APA：
Wu, Xinyu,Li, Jingru,Sun, Guihu,Yang, Jun,Peng, Yunzhu...&Wang, Luqiao.(2023).Role of LncRNAs in the Pathogenesis of Coronary Artery Disease.REVIEWS IN CARDIOVASCULAR MEDICINE,24,(4)
MLA：
Wu, Xinyu,et al."Role of LncRNAs in the Pathogenesis of Coronary Artery Disease".REVIEWS IN CARDIOVASCULAR MEDICINE 24..4(2023)
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