机构：[1]Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, PR China[2]The First Affiliated Hospital, Department of Urology, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, PR China[3]Organ Transplantation Center, The First Affiliated Hospital, Kunming Medical University, Kunming, Yunnan, 650032, PR China外科科室器官移植中心昆明医科大学附属第一医院[4]School of Resources & Environment and Safety Engineering, University of South China, Hengyang, Hunan 421001, PR China[5]The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, PR China
Renal cell carcinoma (RCC) represents a malignant tumor of the urinary system. Individuals with early-stage RCC could be cured by surgical treatment, but a considerable number of cases of advanced RCC progress to drug resistance. Recently, numerous reports have demonstrated that a variety of non-coding RNAs (ncRNAs) contribute to tumor occurrence and development. ncRNAs can act as oncogenic or tumor suppressor genes to regulate proliferation, migration, drug resistance and other processes in RCC cells through a variety of signaling pathways. Considering the lack of treatment options for advanced RCC after drug resistance, ncRNAs may be a good choice as biomarkers of drug resistance in RCC and targets to overcome drug resistance. In this review, we discussed the effects of ncRNAs on drug resistance in RCC and the great potential of ncRNAs as a biomarker of or a new therapeutic method in RCC.
基金：
Hunan Provincial Health and Family Planning Commission Project [A2017017]; Science and Technology Planning Project of Hengyang [202010021604]
语种：
外文
被引次数：
WOS：
PubmedID：
中科院(CAS)分区：
出版当年[2024]版：
无
最新[2023]版：
大类|2 区医学
小类|1 区药学2 区医学：研究与实验
JCR分区：
出版当年[2023]版：
Q1MEDICINE, RESEARCH & EXPERIMENTALQ1PHARMACOLOGY & PHARMACY
最新[2023]版：
Q1MEDICINE, RESEARCH & EXPERIMENTALQ1PHARMACOLOGY & PHARMACY
第一作者机构：[1]Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, PR China
通讯作者：
推荐引用方式(GB/T 7714)：
Liu Yiqi,Zhang Hu,Fang Yuan,et al.Non-coding RNAs in renal cell carcinoma: Implications for drug resistance[J].BIOMEDICINE & PHARMACOTHERAPY.2023,164:doi:10.1016/j.biopha.2023.115001.
APA：
Liu, Yiqi,Zhang, Hu,Fang, Yuan,Tang, Dongshan&Luo, Zhigang.(2023).Non-coding RNAs in renal cell carcinoma: Implications for drug resistance.BIOMEDICINE & PHARMACOTHERAPY,164,
MLA：
Liu, Yiqi,et al."Non-coding RNAs in renal cell carcinoma: Implications for drug resistance".BIOMEDICINE & PHARMACOTHERAPY 164.(2023)
医学