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Expert Consensus on Ion Channel Drugs for Chronic Pain Treatment in China

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机构: [1]Department of Algology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China [2]Department of Algology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China [3]Department of Algology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People’s Republic of China [4]Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People’s Republic of China [5]Department of Algology, The Affiliated Hospital of Qingdao University, Qingdao, People’s Republic of China [6]Pain Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, People’s Republic of China [7]Department of Pain Medicine, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, People’s Republic of China [8]Department of Algology, Xijing Hospital, The Fourth Military Medical University, Xian, People’s Republic of China [9]Department of Neurosurgery, Shenzhen University General Hospital, Shenzhen, People’s Republic of China [10]Department of Algology, The First Affiliated Hospital, Xi’an Jiaotong University, Xi’an, People’s Republic of China [11]Department of Algology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People’s Republic of China [12]Department of Algology, The Yibin First People’s Hospital Affiliated Chongqing Medical University, Yibin, People’s Republic of China [13]Department of Algology, The First Affiliated Hospital of Kunming Medical University, Kunming, People’s Republic of China [14]Department of Algology. Hospital (T.C.M) Affiliated to Southwest Medical University, Luzhou, People’s Republic of China [15]Department of Algology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China
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关键词: chronic pain ion channel drugs voltage -gated calcium channels voltage -gated sodium channel

摘要:
Ion channel drugs have been increasing used for chronic pain management with progress in the development of selective calcium channel modulators. Although ion channel drugs have been proven safe and effective in clinical practice, uncertainty remains regarding its use to treat chronic pain. To standardize the clinical practice of ion channel drug for the treatment of chronic pain, the National Health Commission Capacity Building and Continuing Education Center for Pain Diagnosis and Treatment Special Ability Training Project established an expert group to form an expert consensus on the use of ion channel drugs for the treatment of chronic pain after repeated discussions on existing medical evidence combined with the well clinical experience of experts. The consensus provided information on the mechanism of action of ion channel drugs and their recommendations, caution use, contraindications, and precautions for their use in special populations to support doctors in their clinical decision-making.

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大类 | 3 区 医学
小类 | 3 区 临床神经病学
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Q2 CLINICAL NEUROLOGY

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第一作者机构: [1]Department of Algology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China [*1]Department of Algology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University school of medicine, Shanghai, 200092, People’s Republic of China
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通讯机构: [1]Department of Algology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China [15]Department of Algology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China [*1]Department of Algology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University school of medicine, Shanghai, 200092, People’s Republic of China [*2]Department of Algology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100070, People’s Republic of China
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