国家自然科学基金资助项目,Nos.81160055,81260074%云南省卫生厅卫生系统学科带头人培养计划基金资助项目,No.D-201215%云南省社会发展科技计划基金资助项目,No.2013CA021%云南省消化疾病研究所基金资助项目,No.2014NS123.National Natural Science Foundation of China,Nos.81160055 and 81260074%Medical Academic Leader Training Program of Yunnan Provincial Health Bureau,No.D-201215%Social Development Science and Technology Project of Yunnan Province,No.2013CA021%Foundation of Yunnan Institute of Digestive Disease,No.2014NS123.