Background: Although polyacrylamide hydrogel (PAAG) injection for breast augmentation has been prohibited for many years, the long-term complications will be significant for a long period. Few research articles have focused on the clinicopathological analysis. Materials and Methods: We summarized clinical and pathological features of 90 cases after PAAG-injected breast augmentation, including 2 cases of breast cancer developed following PAAG injection. Results: All patients were females between the ages of 30 and 64 years (mean, 44 years). The complications included masses (75.58%), pain (45.35%), migration (22.09%), deformation (18.60%), infection (16.28%), induration (4.65%), and psychological fear (2.33%). Microscopically, the PAAG presented as purple gel pools, and the foreign body reaction was noted in all 90 patients. The proportion of fibrous component exceeded 90% in 26 cases (28.89%). Chronic and acute inflammation was noted in 70 (77.78%) and 9 (10%) patients, respectively. The mammary gland around the gel displayed atrophy in 18 cases (20.00%), adenosis in 33 cases (36.67%), ductal carcinoma in situ in 1 case (1.11%), and invasive carcinoma in 1 case (1.11%). Conclusion: The long-term complications of PAAG-injected breast augmentation are various and complex. Pathologically, these complications are associated with foreign body reaction, fibrosis, and inflammation. (c) 2019 S. Karger AG, Basel
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81460298]; Scientific Research Foundation of the Education Department of Yunnan Province [2017YJS083]
第一作者机构:[1]Kunming Med Univ, Affiliated Hosp 1, Dept Pathol, Kunming, Yunnan, Peoples R China
通讯作者:
通讯机构:[3]Kunming Med Univ, Affiliated Hosp 1, Dept Plast Surg, 295 Xichang Rd, Kunming 650032, Yunnan, Peoples R China
推荐引用方式(GB/T 7714):
Yang Ying,Li Shumo,He Jia,et al.Clinicopathological Analysis of 90 Cases of Polyacrylamide Hydrogel Injection for Breast Augmentation Including 2 Cases Followed by Breast Cancer[J].BREAST CARE.2020,15(1):38-43.doi:10.1159/000499832.
APA:
Yang, Ying,Li, Shumo,He, Jia,Zhao, Xian,Chen, Wei...&Liu, Liu.(2020).Clinicopathological Analysis of 90 Cases of Polyacrylamide Hydrogel Injection for Breast Augmentation Including 2 Cases Followed by Breast Cancer.BREAST CARE,15,(1)
MLA:
Yang, Ying,et al."Clinicopathological Analysis of 90 Cases of Polyacrylamide Hydrogel Injection for Breast Augmentation Including 2 Cases Followed by Breast Cancer".BREAST CARE 15..1(2020):38-43