机构：[1]State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming 650201, China[2]Institute of Medicinal Chemistry and Chemical Biology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China[3]Department of Dermatology, The First Affiliated Hospital of Kunming Medical University, Kunming 650032, China内科科室皮肤科昆明医科大学附属第一医院
Japonicones A-C (1-3), three new dimeric lindenane-type sesquiterpenoids featuring a rare 12-membered ring framework, were isolated from the whole plants of Chloranthus japonicus Sieb. Their structures and absolute configurations were unequivocally established by a combination of spectroscopic data, ECD calculation, and X-ray crystallography. Compounds 1-3 were evaluated for their DNA Topoisomerase I (Top1) inhibitory, cytotoxic, and antibacterial activities. (C) 2019 Elsevier Ltd. All rights reserved.
基金：
National Scientific and Technological Projects of Yunnan Province [2017FB128]; Foundation of Yunnan Key Laboratory of Natural Medicinal Chemistry [S2017-ZZ08]; Key Research and Development Plan of Yunnan Province-Special Project of Science and Technology in Yunnan Province [201716007]; Major Biomedical Project of Yunnan Province [2018ZF005]; Innovation Team of the ministry of Education [IRT17-R49]; NSFC Joint Foundation of Yunnan Province [U1802287]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [31570363, 31770391]
第一作者机构：[1]State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming 650201, China
通讯作者：
推荐引用方式(GB/T 7714)：
Yan Huan,Qin Xu-Jie,Li Xu-Hong,et al.Japonicones A-C: Three lindenane sesquiterpenoid dimers with a 12-membered ring core from Chloranthus japonicus[J].TETRAHEDRON LETTERS.2019,60(10):713-717.doi:10.1016/j.tetlet.2019.01.040.
APA：
Yan, Huan,Qin, Xu-Jie,Li, Xu-Hong,Yu, Qian,Ni, Wei...&Liu, Hai-Yang.(2019).Japonicones A-C: Three lindenane sesquiterpenoid dimers with a 12-membered ring core from Chloranthus japonicus.TETRAHEDRON LETTERS,60,(10)
MLA：
Yan, Huan,et al."Japonicones A-C: Three lindenane sesquiterpenoid dimers with a 12-membered ring core from Chloranthus japonicus".TETRAHEDRON LETTERS 60..10(2019):713-717
