机构:[1]Department of Neurology, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan, 410008, China[2]Department of Neurology, First Affiliated Hospital, Kunming Medical University, 295 Xi Chang Road, Kunming, Yunnan, 650032, China内科科室神经内科昆明医科大学附属第一医院[3]Department of Neurology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA
Epilepsy is a prevalent neurologic disorder affecting approximately 50 million people worldwide. Cognitive dysfunction induced by seizures is one of the severe comorbidities of epilepsy and epileptic syndrome, which has a negative impact on epileptic patients' quality of life. Several mechanisms may be associated with cognitive impairment in patients with epilepsy. Here, we review how the dynamic functional alterations of brain network influence seizure-related cognitive outcomes.
基金:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81771407, 81601134]; Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2016JJ3157]; Doctoral Scientific Research Foundation of First Affiliated Hospital of Kunming Medical University [2015BS007]