机构：[1]Division of Neonatology, Children’s Hospital of Fudan University, Shanghai, China[2]Division of Neonatology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China[3]Division of Neonatology, First Affiliated Hospital of Kunming Medical University, Kunming, China昆明医科大学附属第一医院[4]Division of Neonatology, Third Affiliated Hospital of Anhui Medical University, Hefei, China[5]Division of Neonatology, Zhangzhou Hospital of Fujian Medical University, Zhangzhou, China[6]Division of Neonatology, The First Hospital of Jilin University, Changchun, China[7]Division of Neonatology, Xiamen Maternity and Child Care Hospital, Xiamen, China[8]Division of Neonatology, Handan Central Hospital, Handan, China[9]Division of Neonatology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China[10]Division of Neonatology, The Northwest Women and Children’s Hospital, Xi’an, China[11]Division of Neonatology, Guiyang Maternal and Child Health Care Hospital, Guiyang, China[12]Division of Neonatology, Ningbo Women and Children’s Hospital, Ningbo, China
Objective: To identify the effect of pregnancy induced hypertension on neonatal outcomes in early and moderate preterm infants of gestational age less than 34 weeks. Study design: Prospectively collected data in 773 premature deliveries less than 34 weeks from 10 centers in China between July 2014 and July 2016 were analyzed in this cohort study. Univariate and Multivariate regression analyses were conducted to exam the effect of pregnancy induced hypertension on neonatal outcomes, including mortality to discharge, intrauterine growth restriction, severe brain injury, neonatal respiratory distress syndrome, bronchopulmonary dysplasia, necrotizing enterocolitis, early onset of sepsis and retinopathy of prematurity. Results: The incidence of PIH in this cohort was 18.4%. Women with PIH tended to have a higher cesarean delivery rate (78.2% vs 40.9%, P < 0.001). More tocolytics and magnesium sulfate were used in PIH women (72.5% vs 48.7%, P < 0.001; 59.2% vs 34.7%, P < 0.001). Mean birth weight was lower in infants of PIH mothers than infants of non-PIH mothers (1522.1 +/- 348.8 g vs 1683.4 +/- 345.3, P < 0.001). In multivariate regression models, PIH was associated with increased risk of IUGR (OR 8.402; 95% CI 4.350-16.227) and lower odds of NRDS (OR 0.526; 95% CI 0.332-0.853). Conclusion: Preterm infants less than 34 weeks born to PIH women had a higher risk of intrauterine growth restriction and lower birth weight PIH warrants more intensive interventions to prevent relevant infant morbidities.
第一作者机构：[1]Division of Neonatology, Children’s Hospital of Fudan University, Shanghai, China[2]Division of Neonatology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China
通讯作者：
通讯机构：[*1]Children’s Hospital of Fudan University, No. 399 Wanyuan Road, Minghang District, Shanghai 201102, China
推荐引用方式(GB/T 7714)：
Lu Cheng-Qiu,Lin Jie,Yuan Lin,et al.Pregnancy induced hypertension and outcomes in early and moderate preterm infants[J].PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH.2018,14:68-71.doi:10.1016/j.preghy.2018.06.008.
APA：
Lu, Cheng-Qiu,Lin, Jie,Yuan, Lin,Zhou, Jian-Guo,Liang, Kun...&Chen, Chao.(2018).Pregnancy induced hypertension and outcomes in early and moderate preterm infants.PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH,14,
MLA：
Lu, Cheng-Qiu,et al."Pregnancy induced hypertension and outcomes in early and moderate preterm infants".PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH 14.(2018):68-71
