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Plantagiolides K-N, three new withanolides and one withanolide glucoside from Tacca plantaginea

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机构: [1]State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China [2]University of Chinese Academy of Sciences, Beijing 100049, China [3]Department of Dermatology, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China [4]Research Institute of Resource Insects, Chinese Academy of Forestry, Kunming 650224, China
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关键词: Tacca plantaginea Withanolide Withanolide glycoside Plantagiolides K-N Cytotoxicity

摘要:
Phytochemical investigation of the whole plants of Tacca plantaginea led to the isolation of 3 new withanolides and one new withanolide glucoside, named plantagiolides K-N (1-4), together with one known withanolide, 4 known withanolide glucosides, and 2 known taccalonolides. Their structures were elucidated by extensive spectroscopic analysis. Compound 4 is the first withanolide glycoside which the sugar moiety is attached at C-7. The effects of the some of isolates on TNFa-induced NF-kappa B transcriptional activity and cytotoxicity were evaluated. (C) 2015 Elsevier B.V. All rights reserved.

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出版当年[2016]版:
大类 | 3 区 医学
小类 | 3 区 药物化学 3 区 药学
最新[2023]版:
大类 | 3 区 医学
小类 | 3 区 药物化学 3 区 药学
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出版当年[2015]版:
Q2 PHARMACOLOGY & PHARMACY Q3 CHEMISTRY, MEDICINAL
最新[2023]版:
Q3 CHEMISTRY, MEDICINAL Q3 PHARMACOLOGY & PHARMACY

影响因子: 最新[2023版] 最新五年平均 出版当年[2015版] 出版当年五年平均 出版前一年[2014版] 出版后一年[2016版]

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第一作者机构: [1]State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China [2]University of Chinese Academy of Sciences, Beijing 100049, China
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