机构：[1]Department of Pathophysiology, Sichuan North Medical College, Nanchong 637100, People’s Republic of China[2]Department of General Surgery, The Seventh People’s Hospital of Chengdu, Chengdu 610041, People’s Republic of China[3]Department of Respiratory Diseases, First Affiliated Hospital, Kunming Medical University, Kunming 650032, People’s Republic of China内科科室呼吸内科昆明医科大学附属第一医院[4]Department of Respiratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, People’s Republic of China四川大学华西医院
The ubiquitin-proteasome system plays an important role in various celluar processes. WWP2, a recently identified ubiquitin E3 ligase, has been proved a multifunctional gene by degradation a series of targets via ubiquitin-dependent proteasome system, including PETN, Smads, Oct4, EGR2, TIRF and so. Hereafter, we reviewed the recent research process about the function of WWP2.
基金：
Major Cultivated Project of Youth Science and Technology Fund in Sichuan North Medical College [CBY11-A-ZP15]
